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Table 1 Characteristics of the study patients between the primary cohort and the validation cohort

From: A novel nomogram for predicting 3-year mortality in critically ill patients after coronary artery bypass grafting

Variables

Total

Primary cohort

Validation cohort

P value

 

(n = 2929)

(n = 2050)

(n = 879)

 

Basic demographics

    

 Age, years

68.6 (60.1–76.2)

68.6 (60.0–76.2)

68.9 (60.3–76.4)

0.375

 Gender, female

781 (26.7)

539 (26.3)

242 (27.5)

0.516

Comorbidities, n (%)

    

 CHF

764 (26.1)

540 (26.3)

224 (25.5)

0.661

 Renal failure

209 (7.1)

153 (7.5)

56 (6.4)

0.330

 Diabetes

1110 (37.9)

791 (38.6)

319 (36.3)

0.258

 Previous myocardial infarction

551 (18.8)

385 (18.8)

166 (18.9)

0.988

 Previous stroke

40 (1.4)

34 (1.7)

6 (0.7)

0.056

24 h vital signs

    

 Mean SBP, mmHg

111.4 (105.8–119.0)

111.4 (105.8–119.1)

111.5 (106.0–118.8)

0.542

 Mean DBP, mmHg

56.1 (52.6–60.5)

56.1 (52.6–60.4)

56.3 (52.6–60.6)

0.626

 Mean HR, beats/min

85.2 (79.4–91.1)

85.3 (79.5–91.1)

85.0 (78.9–91.2)

0.266

 Mean respiratory rate, beats/minute

16.7 (15.0–18.8)

16.7 (15.0–18.7)

16.7 (15.1–18.9)

0.528

 Mean MBP, mmHg

74.3 (70.8–79.0)

74.3 (70.6–78.9)

74.4 (71.0–79.2)

0.425

Laboratory parameters

    

 Hemoglobin, g/dL

10.0 (8.9–11.2)

10.1 (8.9–11.3)

10.0 (8.9–11.2)

0.473

 WBC, 109/L

11.9 (9.2–15.4)

12.0 (9.2–15.5)

11.6 (9.0–15.2)

0.300

 Lactate, mg/dL

2.2 (1.5–3.2)

2.3 (1.6–3.2)

2.1 (1.5–3.1)

0.043

 Anion gap, mmol/L

12.0 (11.0–14.0)

12.0 (11.0–14.0)

12.0 (11.0–14.0)

0.650

 Phosphoric acid, mg/dL

3.5 (2.9–4.1)

3.4 (2.8–4.0)

3.5 (3.0–4.2)

0.025

 APTT, second

35.5 (30.6–44.7)

35.5 (30.5–44.7)

35.4 (30.7–44.6)

0.631

 BUN, mg/dL

16.0 (12.0–20.0)

15.0 (12.0–20.0)

16.0 (12.0–20.0)

0.884

 ALT, U/L

25.5 (17.0–39.8)

24.0 (17.0–40.5)

26.0 (17.0–38.0)

0.767

 AST, U/L

44.0 (26.0–92.5)

44.0 (26.0–91.0)

46.0 (27.0–99.0)

0.516

 PA, mg/dL

3.5 (2.9–4.1)

3.5 (3.0–4.2)

3.4 (2.8–4.0)

0.025

 Creatinine, U/L

0.8 (0.7–1.0)

0.8 (0.7–1.0)

0.8 (0.7–1.0)

0.742

 Platelet, 109/L

158.0 (122.0–204.0)

160.0 (123.0–205.0)

156.0 (120.5–199.5)

0.166

 Potassium, mmol/L

4.3 (3.9–5.0)

4.3 (3.9–5.0)

4.3 (3.9–5.0)

0.733

 Sodium, mmol/L

137.0 (135.0–139.0)

137.0 (135.0–139.0)

137.0 (135.0–138.0)

0.081

 PCO2 (mmHg)

40.0 (37.0–45.0)

40.0 (37.0–45.0)

40.0 (37.0–44.0)

0.816

 PO2 (mmHg)

338.0 (261.0–403.0)

335.0 (259.0–400.0)

345.0 (268.2–410.8)

0.060

 SpO2 (%)

97.0 (78.0–98.0)

97.0 (79.0–98.0)

97.0 (78.0–98.0)

0.169

 pH

7.4 (7.4–7.4)

7.4 (7.4–7.4)

7.4 (7.4–7.4)

0.726

In-hospital management, n (%)

    

 Mechanical ventilation

2771 (94.6)

1940 (94.6)

831 (94.5)

0.988

 RRT

46 (1.6)

34 (1.7)

12 (1.4)

0.672

 Vasopressor use

2473 (84.4)

1733 (84.5)

740 (84.2)

0.854

 1-year mortality, n (%)

203 (6.9)

137 (6.7)

66 (7.5)

0.467

 3-year mortality, n (%)

378 (12.9)

265 (12.9)

113 (12.9)

1.000

  1. CHF congestive heart failure; SBP systolic blood pressure; DBP diastolic blood pressure; HR heart rate; MBP mean blood pressure; WBC white blood cell; APTT activated partial thromboplastin time; BUN blood urea nitrogen; ALT alanine aminotransferase; AST glutamic oxalacetic transaminase; PA phosphoric acid; RRT renal replacement treatment; OASIS Oxford Acute Severity of Illness Score; SOFA Sequential Organ Failure Assessment; SAPS II Simplified Acute Physiology Score II
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