Skip to main content

Table 2 Compliance with Therapeutic Guidelines: Antibiotics recommendations

From: Surgical antimicrobial prophylaxis in open reduction internal fixation procedures at a metropolitan hospital in Australia: a retrospective audit

Summary of Therapeutic Guidelines recommendations

Compliance with version 15 guidelines (2018)

Compliance with version 16 guidelines (2019)

All patients should receive preoperative antibiotics for internal fixations

97.3% (180/185)

95.6% (196/205)

Antimicrobial choice

 Cefazolin

97.7% (176/180)

99.5% (195/196)

 Vancomycin (for patients with immediate hypersensitivity to penicillin)

0% (0/4)a

0% (0/1)a

Dose (of cefazolin)

 2 g or as appropriateb

80.6% (145/180)

83.2% (163/196)

Preoperative timing of administration

 Within 60 min prior to incision (for cefazolin) or within 120 min prior to incision (for vancomycin)

Not available

Not available

Route

 IV

100% (180/180)

100% (196/196)

Intraoperative drug administration if duration of procedure ≥ 240 min

0% (0/2)

100% (2/2)

Duration of prophylaxis

 Should not exceed 24 h from time of induction (version 15)

78.3% (141/180)

 Patients should receive only a single preoperative dose (version 16)

20.4% (40/196)

  1. aPatients received clindamycin instead of vancomycin
  2. bAppropriate dose based on age, weight, or renal function