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Table 2 Compliance with Therapeutic Guidelines: Antibiotics recommendations

From: Surgical antimicrobial prophylaxis in open reduction internal fixation procedures at a metropolitan hospital in Australia: a retrospective audit

Summary of Therapeutic Guidelines recommendations Compliance with version 15 guidelines (2018) Compliance with version 16 guidelines (2019)
All patients should receive preoperative antibiotics for internal fixations 97.3% (180/185) 95.6% (196/205)
Antimicrobial choice
 Cefazolin 97.7% (176/180) 99.5% (195/196)
 Vancomycin (for patients with immediate hypersensitivity to penicillin) 0% (0/4)a 0% (0/1)a
Dose (of cefazolin)
 2 g or as appropriateb 80.6% (145/180) 83.2% (163/196)
Preoperative timing of administration
 Within 60 min prior to incision (for cefazolin) or within 120 min prior to incision (for vancomycin) Not available Not available
Route
 IV 100% (180/180) 100% (196/196)
Intraoperative drug administration if duration of procedure ≥ 240 min 0% (0/2) 100% (2/2)
Duration of prophylaxis
 Should not exceed 24 h from time of induction (version 15) 78.3% (141/180)
 Patients should receive only a single preoperative dose (version 16) 20.4% (40/196)
  1. aPatients received clindamycin instead of vancomycin
  2. bAppropriate dose based on age, weight, or renal function