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Table 1 Clinical characteristics of the pre-TG18 group and post-TG18 group

From: Laparoscopic subtotal cholecystectomy after percutaneous transhepatic gallbladder drainage for grade II or III acute cholecystitis

Variable

Pre-TG18 group (2013–2017, n = 17)

Post-TG18 group (2018–2020, n = 27)

P-value

Age (years), median [IQR]

75 [63–84]

78 [68–87]

0.682

Sex Male

6 (35.3%)

18 (66.7%)

0.042*

Severity grade of AC

0.234

 II

16 (94.1%)

22 (81.5%)

 

 III

1 (5.9%)

5 (18.5%)

 

ASA-PS

0.143

 I–II

12 (70.6%)

13 (48.1%)

 

 III or higher

5 (29.4%)

14 (51.9%)

 

SIRS

10 (58.8%)

18 (66.7%)

0.599

WBC count on admission × 103/μL, median [IQR]

13.1 [10.7–20.6]

14.9 [11.9–19.7]

0.736

CCI on admission

1 [0–2.5]

2 [1–3]

0.219

Comorbidity

 

 MI

5 (29.4%)

6 (22.2%)

0.592

 CHF

1 (5.9%)

4 (14.8%)

0.363

 Peripheral vascular disease

0

3 (11.1)

0.155

 Cerebrovascular disease

3 (17.6%)

5 (18.5%)

0.942

 Dementia

3 (17.6%)

6 (22.2%)

0.714

 RA

0

2 (7.4%)

0.251

 Diabetes

5 (29.4%)

8 (29.6%)

0.988

 Hemiplegia

0

4 (14.8%)

0.096

 CKD

0

2 (7.4%)

0.251

 Solid tumor

1 (5.9%)

2 (7.4%)

0.845

 Lymphoma

1 (5.9%)

0

0.202

Time from onset to PTGBD, days, median [IQR]

3 [1–7]

2 [1–3]

0.126

Time from PTGBD to cholecystectomy, days, median [IQR]

8 [4–11]

15 [9–42]

0.010*

  1. TG18 Tokyo Guidelines 2018, AC acute cholecystitis, ASA-PS American Society of Anesthesiologists physical status, SIRS systemic inflammatory response syndrome, WBC white blood cell, CCI Charlson Comorbidity Index, MI myocardial infarction, CHF congestive heart failure, RA rheumatoid arthritis, CKD chronic kidney disease, PTGBD percutaneous transhepatic gallbladder drainage, IQR interquartile range
  2. Values are presented as n (%) or median [IQR, 25th and 75th percentile], as appropriate
  3. *P values significant at (P < 0.05)