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Table 3 Associations between surgical factors and patients with or without anastomotic leakage

From: Preoperative C-reactive protein to albumin ratio predicts anastomotic leakage after esophagectomy for thoracic esophageal cancer: a single-center retrospective cohort study

  

All case

Group NAL

Group AL

 
  

N = 295

N = 261

N = 34

p value

Thoracic procedure

MIE

220 (74.6%)

192 (75.6%)

28 (82.4%)

0.268

 

Open

75 (25.4%)

69 (26.4%)

6 (17.6%)

 

Abdominal procedure

HALS

277 (93.9%)

246 (94.3%)

31 (91.2%)

0.447*

 

Open

18 (6.1%)

15 (5.7%)

3 (8.8%)

 

Lymoph node dissection

Three-field

278 (94.3%)

248 (95.0%)

30 (88.2%)

0.118*

 

Two-field

17 (5.8%)

13 (5.0%)

4 (11.8%)

 

Operation time

(minutes, IQR)

561 (509–613)

556 (506–611)

598 (550–636)

0.02

 

 > 565

137 (46.4%)

114 (43.7%)

23 (67.7%)

0.008

 

 ≤ 565

158 (53.6%)

147 (56.3%)

11 (32.4%)

 

Blood loss

(mL, IQR)

300 (190–550)

275 (180–540)

335 (223–743)

0.078

 

 ≥ 480

85 (28.8%)

70 (26.8%)

15 (44.1%)

0.036

 

 < 480

210 (71.2%)

191 (73.2%)

19 (55.9%)

 

Anastomosis method

Hand-sewn

160 (54.2%)

144 (55.2%)

16 (47.1%)

0.372

 

Mechanical

135 (45.8%)

117 (44.8%)

18 (52.9%)

 

Reconstruction route

Retrosternal

178 (60.3%)

157 (60.2%)

21 (61.8%)

0.856

 

Posterior mediastinal

117 (39.7%)

104 (39.8%)

13 (38.4%)

 

Residual tumor

R0

285 (96.6%)

251 (96.2%)

34 (100%)

0.612*

 

R1

10 (3.4%)

10 (3.8%)

0 (0.0%)

 

Timing of surgery

2007–2014

125 (42.4%)

110 (42.2%)

15 (44.1%)

0.827

 

2015–2020

170 (57.6%)

151 (57.9%)

19 (55.9%)

 
  1. *Fisher's exact test
  2. IQR interquartile range;
  3. MIE minimally invasive esophagectomy, HALS hand-assisted laparoscopic surgery
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