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Table 5 Univariate and multivariate analyses of prognostic factors for recurrence-free survival in a propensity score matched cohort

From: Postoperative controlling nutritional status score is an independent risk factor of survival for patients with small hepatocellular carcinoma: a retrospective study

Factors Univariate analysis Multivariate analysis
HR (95 %CI) P HR (95 %CI) P
Age 0.996 (0.977–1.014) 0.638   
Gender (male) 1.449 (0.855–2.455) 0.168   
HBsAg (+) 1.439 (0.633–3.272) 0.385   
AFP (> 400ng/mL) 1.310 (0.896–1.915) 0.163   
TBIL 0.998 (0.962–1.036) 0.919   
ALT 1.008 (1.001–1.016) 0.030   
AST 1.013 (1.002–1.024) 0.025   
PT 1.093 (0.933–1.280) 0.271   
CREA 1.017 (1.001–1.034) 0.039   
HGB 1.002 (0.988–1.016) 0.832   
PLT 0.997 (0.991–1.003) 0.387   
WBC 0.951 (0.821–1.102) 0.951   
PreCONUT (≥ 3) 0.911 (0.631–1.317) 0.622   
Tumor size (3–5 cm) 0.939 (0.656–1.344) 0.731   
Tumor number (2–3) 1.684 (1.050–2.701) 0.030 1.611 (1.003–2.589) 0.049
Blood loss 1.001 (0.998–1.002) 0.834   
Transfusion (+) 1.167 (0.898–3.110) 0.105   
Cirrhosis (+) 1.352 (0.707–2.585) 0.363   
Operation duration 1.072 (0.864–1.582) 0.461   
Operation type (major) 1.212 (0.889–1.634) 0.573   
MVI (+) 2.169 (1.461–3.221) < 0.001 1.963 (1.314–2.933) 0.001
Poor differentiation (+) 1.579 (1.095–2.277) 0.014 1.588 (1.098–2.298) 0.014
Hospital stay 1.004 (0.984–1.021) 0.641   
PoCONUT (≥ 3) 1.561 (1.088–2.239) 0.015 1.639 (1.139–2.358) 0.008
  1. CONUT controlling nutritional status, PreCONUT preoperative CONUT, PoCONUT postoperative CONUT, HBsAg hepatitis B viral surface antigen, AFP alpha-fetoprotein, TBIL total bilirubin, ALT alanine aminotransferase, AST aspartate aminotransferase, PT prothrombin time, CREA creatinine, HGB hemoglobin, PLT platelet count, WBC white blood cell count; MVI microvascular invasion, HR hazard ratio, CI confidence interval