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Table 3 Clinical characteristics of Clinical hypoPT

From: Role of the 2018 American Thyroid Association statement on postoperative hypoparathyroidism: a 5-year retrospective study

Index

No hypoPT (N = 1043)

Transient hypoPT (N = 72)

Permanent hypoPT (N = 55)

P1

P2

Age

41.06 ± 11.05

41.88 ± 13.45

40.89 ± 13.37

0.615

0.683

 ≥ 55 years

109 (10.5)

15 (20.8)

9 (16.4)

0.007*

0.524

Gender

     

Male

333 (31.9)

16 (22.2)

13 (23.6)

0.086

0.851

Female

710 (68.1)

56 (77.8)

42 (76.4)

0.086

0.851

131I

546 (52.3)

38 (52.8)

36 (65.5)

0.944

0.151

BMI

23.23 ± 4.12

23.29 ± 3.06

23.07 ± 3.88

0.910

0.728

> 24

376 (36.6)

29 (42.0)

18 (32.7)

0.364

0.289

Hypertension

84 (8.1)

6 (8.3)

3 (5.5)

0.933

0.731

Diabetes

31 (3.0)

2 (2.8)

2 (3.6)

1

1

Hypothyroidism

14 (1.3)

1 (1.4)

1 (1.8)

1

1

Hyperthyroidism

27 (2.6)

1 (1.4)

0 (0)

1

1

HD

229 (22.0)

12 (16.7)

15 (27.3)

0.292

0.148

NG

541 (51.9)

31 (43.1)

30 (54.5)

0.148

0.199

Pre PTH

4.96 ± 1.10

4.91 ± 1.19

4.82 ± 1.10

0.698

0.673

Pre Ca

2.35 ± 0.14

2.32 ± 0.10

2.32 ± 0.10

0.042*

0.925

Pre Mg

0.89 ± 0.09

0.91 ± 0.18

0.88 ± 0.08

0.192

0.305

Pre P

1.12 ± 0.20

1.12 ± 0.20

1.14 ± 0.17

0.893

0.508

Pre 25-OH-VD

45.81 ± 17.02

46.79 ± 16.08

48.53 ± 27.66

0.759

0.788

Carbon nanoparticles

787 (75.5)

45 (62.5)

41 (74.5)

0.015*

0.150

Unintentionally resected PGs

0.09 ± 0.35

0.08 ± 0.28

0.13 ± 0.34

0.799

0.422

≥ 1PG

83 (8.0)

6 (8.3)

7 (12.7)

0.909

0.418

Autotransplanted PGs

0.99 ± 0.77

1.29 ± 0.70

1.13 ± 0.70

0.001*

0.191

No PG

298 (28.6)

9 (12.5)

8 (14.5)

0.003*

0.737

1 PG

474 (45.4)

34 (47.2)

34 (61.8)

0.770

0.102

 ≥ 2PGs

271 (26.0)

29 (40.3)

13 (23.6)

0.008*

0.048*

Neck dissection

     

UCND

277 (26.6)

6 (8.3)

7 (12.7)

0.001*

0.418

BCND

766 (73.4)

66 (91.7)

48 (87.3)

0.001*

0.418

ULND

184 (17.6)

16 (22.2)

14 (25.5)

0.327

0.671

BLND

21 (2.0)

4 (5.6)

2 (3.6)

0.072

0.697

Intraoperative blood loss (mL)

44.25 ± 41.11

69.49 ± 111.98

62.10 ± 87.73

0.069

0.699

Intraoperative liquid infusion (mL)

1330 ± 700

1526 ± 705

1678 ± 829

0.028*

0.295

Tumor characteristics

     

Isthmus

48 (4.8)

10 (14.3)

2 (3.6)

0.001*

0.065

Multifocality

142 (14.1)

20 (28.2)

18 (32.7)

0.430

0.696

Bilaterality

245 (24)

11 (15.7)

13 (23.6)

0.716

0.264

Capsular invasion

227 (21.8)

8 (11.1)

14 (25.5)

0.032*

0.034*

Minor ETE

95 (9.1)

7 (55.6)

3 (5.5)

0.863

0.512

Major ETE

56 (5.4)

4 (9.7)

4 (7.2)

0.792

0.726

  1. BMI, Body mass index; HD, Hashimoto’s thyroiditis; NG, Nodular goiter; Pre, preoperative; PTH, Parathyroid Hormone; Ca, calcium; Mg, Magnesium; P, phosphorus; PG, Parathyroid Gland; UCND, unilateral central neck dissection; BCND, bilateral central dissection; ULND, unilateral lateral neck dissection; BLND, bilateral lateral neck dissection; ETE, extrathyroidal extension
  2. *P < 0.05
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