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Table 3 Clinical characteristics of Clinical hypoPT

From: Role of the 2018 American Thyroid Association statement on postoperative hypoparathyroidism: a 5-year retrospective study

Index No hypoPT (N = 1043) Transient hypoPT (N = 72) Permanent hypoPT (N = 55) P1 P2
Age 41.06 ± 11.05 41.88 ± 13.45 40.89 ± 13.37 0.615 0.683
 ≥ 55 years 109 (10.5) 15 (20.8) 9 (16.4) 0.007* 0.524
Gender      
Male 333 (31.9) 16 (22.2) 13 (23.6) 0.086 0.851
Female 710 (68.1) 56 (77.8) 42 (76.4) 0.086 0.851
131I 546 (52.3) 38 (52.8) 36 (65.5) 0.944 0.151
BMI 23.23 ± 4.12 23.29 ± 3.06 23.07 ± 3.88 0.910 0.728
> 24 376 (36.6) 29 (42.0) 18 (32.7) 0.364 0.289
Hypertension 84 (8.1) 6 (8.3) 3 (5.5) 0.933 0.731
Diabetes 31 (3.0) 2 (2.8) 2 (3.6) 1 1
Hypothyroidism 14 (1.3) 1 (1.4) 1 (1.8) 1 1
Hyperthyroidism 27 (2.6) 1 (1.4) 0 (0) 1 1
HD 229 (22.0) 12 (16.7) 15 (27.3) 0.292 0.148
NG 541 (51.9) 31 (43.1) 30 (54.5) 0.148 0.199
Pre PTH 4.96 ± 1.10 4.91 ± 1.19 4.82 ± 1.10 0.698 0.673
Pre Ca 2.35 ± 0.14 2.32 ± 0.10 2.32 ± 0.10 0.042* 0.925
Pre Mg 0.89 ± 0.09 0.91 ± 0.18 0.88 ± 0.08 0.192 0.305
Pre P 1.12 ± 0.20 1.12 ± 0.20 1.14 ± 0.17 0.893 0.508
Pre 25-OH-VD 45.81 ± 17.02 46.79 ± 16.08 48.53 ± 27.66 0.759 0.788
Carbon nanoparticles 787 (75.5) 45 (62.5) 41 (74.5) 0.015* 0.150
Unintentionally resected PGs 0.09 ± 0.35 0.08 ± 0.28 0.13 ± 0.34 0.799 0.422
≥ 1PG 83 (8.0) 6 (8.3) 7 (12.7) 0.909 0.418
Autotransplanted PGs 0.99 ± 0.77 1.29 ± 0.70 1.13 ± 0.70 0.001* 0.191
No PG 298 (28.6) 9 (12.5) 8 (14.5) 0.003* 0.737
1 PG 474 (45.4) 34 (47.2) 34 (61.8) 0.770 0.102
 ≥ 2PGs 271 (26.0) 29 (40.3) 13 (23.6) 0.008* 0.048*
Neck dissection      
UCND 277 (26.6) 6 (8.3) 7 (12.7) 0.001* 0.418
BCND 766 (73.4) 66 (91.7) 48 (87.3) 0.001* 0.418
ULND 184 (17.6) 16 (22.2) 14 (25.5) 0.327 0.671
BLND 21 (2.0) 4 (5.6) 2 (3.6) 0.072 0.697
Intraoperative blood loss (mL) 44.25 ± 41.11 69.49 ± 111.98 62.10 ± 87.73 0.069 0.699
Intraoperative liquid infusion (mL) 1330 ± 700 1526 ± 705 1678 ± 829 0.028* 0.295
Tumor characteristics      
Isthmus 48 (4.8) 10 (14.3) 2 (3.6) 0.001* 0.065
Multifocality 142 (14.1) 20 (28.2) 18 (32.7) 0.430 0.696
Bilaterality 245 (24) 11 (15.7) 13 (23.6) 0.716 0.264
Capsular invasion 227 (21.8) 8 (11.1) 14 (25.5) 0.032* 0.034*
Minor ETE 95 (9.1) 7 (55.6) 3 (5.5) 0.863 0.512
Major ETE 56 (5.4) 4 (9.7) 4 (7.2) 0.792 0.726
  1. BMI, Body mass index; HD, Hashimoto’s thyroiditis; NG, Nodular goiter; Pre, preoperative; PTH, Parathyroid Hormone; Ca, calcium; Mg, Magnesium; P, phosphorus; PG, Parathyroid Gland; UCND, unilateral central neck dissection; BCND, bilateral central dissection; ULND, unilateral lateral neck dissection; BLND, bilateral lateral neck dissection; ETE, extrathyroidal extension
  2. *P < 0.05