Skip to main content

Table 2 Clinical characteristics of Biochemical hypoPT

From: Role of the 2018 American Thyroid Association statement on postoperative hypoparathyroidism: a 5-year retrospective study

Index No hypoPT (N = 1043) Transient hypoPT (N = 363) Permanent hypoPT (N = 8) P1 P2
Age 41.06 ± 11.05 42.67 ± 12.03 46.25 ± 7.87 0.019* 0.403
≥ 55 years 109 (10.5) 55 (15.2) 2 (25.0) 0.016* 0.355
Gender      
Male 333 (31.9) 89 (24.5) 1 (12.5) 0.008* 0.685
Female 710 (68.1) 274 (75.5) 7 (87.5) 0.008* 0.685
131I 546 (52.3) 205 (56.5) 3 (37.5) 0.175 0.307
BMI 23.23 ± 4.12 23.18 ± 3.84 23.69 ± 2.51 0.838 0.709
 > 24 376 (36.6) 125 (35.2) 4 (50.0) 0.645 0.462
Hypertension 84 (8.1) 33 (9.1) 0 (0) 0.538 1
Diabetes 31 (3.0) 9 (2.5) 0 (0) 0.627 1
Hypothyroidism 14 (1.3) 6 (1.7) 0 (0) 0.667 1
Hyperthyroidism 27 (2.6) 13 (3.6) 0 (0) 0.327 1
HD 229 (22.0) 90 (24.8) 1 (12.5) 0.266 0.685
NG 541 (51.9) 193 (53.2) 7 (87.5) 0.670 0.074
Pre PTH 4.96 ± 1.10 4.95 ± 1.07 4.00 ± 1.25 0.878 0.014*
Pre Ca 2.35 ± 0.14 2.36 ± 0.54 2.33 ± 0.15 0.478 0.853
Pre Mg 0.89 ± 0.09 0.91 ± 0.32 0.88 ± 0.04 0.081 0.765
Pre P 1.12 ± 0.20 1.22 ± 1.94 1.13 ± 0.15 0.099 0.895
Pre 25-OH-VD 45.81 ± 17.02 47.91 ± 14.88 56.28 ± 12.51 0.275 0.338
Carbon nanoparticles 787 (75.5) 259 (71.3) 7 (87.5) 0.123 0.450
Unintentionally resected PGs 0.09 ± 0.35 0.19 ± 0.50 0 0.001* 0.000*
≥ 1PG 83 (8.0) 52 (14.3) 0 (0) 0.000* 0.607
Autotransplanted PGs 0.99 ± 0.77 1.24 ± 0.77 0.63 ± 0.52 0.000* 0.025*
No PG 298 (28.6) 66 (18.2) 3 (37.5) 0.000* 0.171
1 PG 474 (45.4) 151 (41.6) 5 (62.5) 0.220 0.289
≥ 2PGs 271 (26.0) 146 (40.2) 0 (0) 0.000* 0.025*
Neck dissection      
UCND 277 (26.6) 65 (17.9) 3 (37.5) 0.001* 0.165
BCND 766 (73.4) 298 (82.1) 5 (62.5) 0.001* 0.165
ULND 184 (17.6) 74 (20.4) 1 (12.5) 0.245 1
BLND 21 (2.0) 14 (3.9) 0 (0) 0.052 1
Intraoperative blood loss (mL) 44.25 ± 41.11 58.11 ± 63.77 17.00 ± 4.47 0.000* 0.151
Intraoperative liquid infusion (mL) 1330 ± 700 1500 ± 685 1208 ± 311 0.000* 0.299
Tumor characteristics      
Isthmus 48 (4.8) 16 (4.5) 0 (0) 0.826 1
Multifocality 142 (14.1) 52 (14.6) 1 (12.5) 0.830 1
Bilaterality 245 (24.0) 80 (22.2) 1 (12.5) 0.516 1
Capsular invasion 227 (21.8) 66 (18.2) 2 (25.0) 0.148 0.642
Minor ETE 95 (9.1) 44 (12.1) 1 (12.5) 0.098 1
Major ETE 56 (5.4) 26 (7.2) 2 (25.0) 0.209 0.116
  1. BMI, Body mass index; HD, Hashimoto’s thyroiditis; NG, Nodular goiter; Pre, preoperative; PTH, Parathyroid Hormone; Ca, calcium; Mg, Magnesium; P, phosphorus; PG, Parathyroid Gland; UCND, unilateral central neck dissection; BCND, bilateral central dissection; ULND, unilateral lateral neck dissection; BLND, bilateral lateral neck dissection; ETE, extrathyroidal extension
  2. *P < 0.05