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Table 2 Clinical characteristics of Biochemical hypoPT

From: Role of the 2018 American Thyroid Association statement on postoperative hypoparathyroidism: a 5-year retrospective study

Index

No hypoPT (N = 1043)

Transient hypoPT (N = 363)

Permanent hypoPT (N = 8)

P1

P2

Age

41.06 ± 11.05

42.67 ± 12.03

46.25 ± 7.87

0.019*

0.403

≥ 55 years

109 (10.5)

55 (15.2)

2 (25.0)

0.016*

0.355

Gender

     

Male

333 (31.9)

89 (24.5)

1 (12.5)

0.008*

0.685

Female

710 (68.1)

274 (75.5)

7 (87.5)

0.008*

0.685

131I

546 (52.3)

205 (56.5)

3 (37.5)

0.175

0.307

BMI

23.23 ± 4.12

23.18 ± 3.84

23.69 ± 2.51

0.838

0.709

 > 24

376 (36.6)

125 (35.2)

4 (50.0)

0.645

0.462

Hypertension

84 (8.1)

33 (9.1)

0 (0)

0.538

1

Diabetes

31 (3.0)

9 (2.5)

0 (0)

0.627

1

Hypothyroidism

14 (1.3)

6 (1.7)

0 (0)

0.667

1

Hyperthyroidism

27 (2.6)

13 (3.6)

0 (0)

0.327

1

HD

229 (22.0)

90 (24.8)

1 (12.5)

0.266

0.685

NG

541 (51.9)

193 (53.2)

7 (87.5)

0.670

0.074

Pre PTH

4.96 ± 1.10

4.95 ± 1.07

4.00 ± 1.25

0.878

0.014*

Pre Ca

2.35 ± 0.14

2.36 ± 0.54

2.33 ± 0.15

0.478

0.853

Pre Mg

0.89 ± 0.09

0.91 ± 0.32

0.88 ± 0.04

0.081

0.765

Pre P

1.12 ± 0.20

1.22 ± 1.94

1.13 ± 0.15

0.099

0.895

Pre 25-OH-VD

45.81 ± 17.02

47.91 ± 14.88

56.28 ± 12.51

0.275

0.338

Carbon nanoparticles

787 (75.5)

259 (71.3)

7 (87.5)

0.123

0.450

Unintentionally resected PGs

0.09 ± 0.35

0.19 ± 0.50

0

0.001*

0.000*

≥ 1PG

83 (8.0)

52 (14.3)

0 (0)

0.000*

0.607

Autotransplanted PGs

0.99 ± 0.77

1.24 ± 0.77

0.63 ± 0.52

0.000*

0.025*

No PG

298 (28.6)

66 (18.2)

3 (37.5)

0.000*

0.171

1 PG

474 (45.4)

151 (41.6)

5 (62.5)

0.220

0.289

≥ 2PGs

271 (26.0)

146 (40.2)

0 (0)

0.000*

0.025*

Neck dissection

     

UCND

277 (26.6)

65 (17.9)

3 (37.5)

0.001*

0.165

BCND

766 (73.4)

298 (82.1)

5 (62.5)

0.001*

0.165

ULND

184 (17.6)

74 (20.4)

1 (12.5)

0.245

1

BLND

21 (2.0)

14 (3.9)

0 (0)

0.052

1

Intraoperative blood loss (mL)

44.25 ± 41.11

58.11 ± 63.77

17.00 ± 4.47

0.000*

0.151

Intraoperative liquid infusion (mL)

1330 ± 700

1500 ± 685

1208 ± 311

0.000*

0.299

Tumor characteristics

     

Isthmus

48 (4.8)

16 (4.5)

0 (0)

0.826

1

Multifocality

142 (14.1)

52 (14.6)

1 (12.5)

0.830

1

Bilaterality

245 (24.0)

80 (22.2)

1 (12.5)

0.516

1

Capsular invasion

227 (21.8)

66 (18.2)

2 (25.0)

0.148

0.642

Minor ETE

95 (9.1)

44 (12.1)

1 (12.5)

0.098

1

Major ETE

56 (5.4)

26 (7.2)

2 (25.0)

0.209

0.116

  1. BMI, Body mass index; HD, Hashimoto’s thyroiditis; NG, Nodular goiter; Pre, preoperative; PTH, Parathyroid Hormone; Ca, calcium; Mg, Magnesium; P, phosphorus; PG, Parathyroid Gland; UCND, unilateral central neck dissection; BCND, bilateral central dissection; ULND, unilateral lateral neck dissection; BLND, bilateral lateral neck dissection; ETE, extrathyroidal extension
  2. *P < 0.05