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Table 2 Factors associated with in-hospital mortality among patients who underwent major abdominal surgery at MNRH during the study period

From: Elevated serum lactate as a predictor of outcomes in patients following major abdominal surgery at a tertiary hospital in Uganda

Characteristic (n = 246)

Univariate

Multivariate

cOR

95% CI

p-value

aOR

95%CI

p-value

Age

      

  < 18 years

1

     

  ≥ 18 years

0.30

0.21–0.43

 < 0.001

0.24

0.06–0.90

0.034

Gender

      

 Male

1

     

 Female

0.23

0.15–0.34

 < 0.001

0.19

0.06–0.64

0.007

Type of surgery

      

 Elective

1

     

 Emergency

2.67

1.98–3.60

 < 0.001

2.27

0.08–2.33

0.331

ASA status

      

 I

1

     

 II

2.98

1.09–3.87

0.020

1.20

0.45–3.22

0.710

 III

3.68

1.76–5.65

0.001

2.06

0.74–4.96

0.078

 IV

6.13

2.89–9.97

 < 0.001

2.39

0.13–4.18

0.462

Duration between diagnosis & surgery for emergencies (days)

      

 Within 1 day

1

     

 Longer than a day

1.77

1.59–2.90

0.043

1.45

1.13–1.86

0.003

Duration of surgery (hours)

      

  ≤ 1.5

1

     

  > 1.5

2.63

1.75–4.00

 < 0.001

3.17

1.01–9.98

0.049

Pre-surgery treatment

      

 Yes

1

     

 No

2.09

1.54–4.03

 < 0.001

1.78

0.29–11.11

0.531

Intraoperative treatment (litres)

      

  ≤ 1

1

     

  > 1

0.30

0.19–0.47

 < 0.001

1.51

0.12–2.69

0.753

Comorbidities

      

 No

1

     

 Yes

1.15

1.10–1.19

 < 0.001

1.23

1.11–1.36

 < 0.001

Organs involved

      

 One

1

     

 More than one organ

1.34

1.20–1.50

 < 0.001

1.06

0.71–1.25

0.675

Serum lactate

      

 Normal (≤ 2.0 mmol/L)

1

     

 High (> 2.0 mmol/L)

3.79

2.09–6.84

 < 0.001

5.20

1.51–17.92

0.009

  1. The bold was indicative of the statistically significant p values of different variables
  2. Mortality n = 34, 13.8%