Bowel functional outcomes | No. of studies | J-pouch | Side-to-end | I2 (%) | Analysis model | OR/WMD | 95% CI | P value | ||
---|---|---|---|---|---|---|---|---|---|---|
Patients | Mean/rate | Patients | Mean/rate | |||||||
Baseline | ||||||||||
Stool frequency | 3 | 122 | 1.1# | 134 | 1.3# | 71 | Random | − 0.19† | − 0.42, 0.03 | 0.09 |
Urgency | 3 | 92 | 11%^ | 97 | 8%^ | 19 | Fixed | 1.32* | 0.52, 3.39 | 0.56 |
Incomplete defecation | 2 | 74 | 4%^ | 74 | 1%^ | 0 | Fixed | 2.39* | 0.34, 16.67 | 0.38 |
Short term | ||||||||||
Stool frequency | 5 | 195 | 2.7# | 208 | 3.0# | 95 | Random | − 0.30† | − 1.04, 0.44 | 0.42 |
Urgency | 4 | 115 | 30%^ | 121 | 41%^ | 0 | Fixed | 0.53* | 0.28, 1.00 | 0.05 |
Incomplete defecation | 3 | 97 | 35%^ | 98 | 27%^ | 0 | Fixed | 1.65* | 0.83, 3.28 | 0.15 |
Medium term | ||||||||||
Stool frequency | 4 | 164 | 2.6# | 173 | 2.9# | 96 | Random | − 0.32† | − 1.10, 0.45 | 0.41 |
Urgency | 3 | 84 | 37%^ | 86 | 48%^ | 42 | Fixed | 0.67* | 0.34, 1.29 | 0.23 |
Incomplete defecation | 2 | 66 | 36%^ | 63 | 51%^ | 31 | Fixed | 0.56* | 0.28, 1.12 | 0.10 |
Long term | ||||||||||
Stool frequency | 3 | 135 | 1.4# | 138 | 1.8# | 91 | Random | − 0.34† | − 0.84, 0.16 | 0.19 |
Urgency | 2 | 55 | 22%^ | 51 | 39%^ | 0 | Fixed | 0.40* | 0.16, 1.01 | 0.05 |
Incomplete defecation | 2 | 55 | 33%^ | 51 | 39%^ | 0 | Fixed | 0.71* | 0.31, 1.62 | 0.41 |