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Table 2 Univariate and multivariate analyses of factors associated with 5-year OS and 5-year DFS

From: No beneficial effect on survival but a decrease in postoperative complications in patients with rectal cancer undergoing robotic surgery: a retrospective cohort study

Variables

5-year OS

5-year DFS

Univariate

Multivariate

P

Univariate

Multivariate

P

P

HR (95% CI)

P

HR (95% CI)

Age

0.024

1.026 (1.005–1.047)

0.014

0.011

0.979 (0.959–0.999)

0.039

Sex (male)

0.369

  

0.066

  

BMI (kg/m2)

0.307

  

0.326

  

CEA

< 0.001

1.016 (1.007–1.026)

0.001

0.058

  

ASA class

0.053

 

0.669

0.032

  

Tumour location

0.036

 

0.054

0.001

0.872 (0.802–0.948)

0.001

With robotic surgery

0.925

  

0.451

  

With previous abdominal surgery

0.065

  

0.583

  

Lymph nodes retrieved

0.332

  

0.036

0.937 (0.888–0.989)

0.018

TNM stage

0.003

1.622 (1.068–2.464)

0.023

0.001

1.919 (1.241–2.969)

0.003

Differentiation grade

0.010

1.664 (1.093–2.535)

0.018

< 0.001

1.660 (1.116–2.469)

0.012

CRM (no involved)

0.302

  

0.754

  

With lymphovascular invasion

0.018

 

0.123

0.005

  
  1. Statistical analysis was performed using a multivariable Cox proportional hazards model. Significant variables from the univariate analysis were included in the multivariate Cox regression models to assess their contribution to 5-year OS and DFS. Variables with a P < 0.05 and hazard ratio (HR) > 20% were kept in the final model
  2. Bold values indicate statistical significance
  3. BMI body mass index, ASA American Society of Anesthesiologists, CRT chemoradiotherapy, TNM tumour node metastasis, CRM circumferential resection margin, OS overall survival, DFS disease-free survival, HR Hazard radio, 95% CI 95% confidence interval