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Table 3 Results of a multivariate analysis to identify predictors for each complication correlated with the drain output volume

From: Drain output volume after pancreaticoduodenectomy is a useful warning sign for postoperative complications

 

Odds ratio

95% CI

p-value

a. Major morbidity

DA on POD1 ≥ 913 (U/l)

2.89

0.573–2.51

0.63

CRP on POD1 ≥ 10.09 (mg/dl)

2.45

1.1–5.47

0.028

DOV on POD3 ≥ 130 (ml)

0.734

0.323–1.67

0.461

DA on POD3 ≥ 96 (U/l)

2.89

1.46–5.73

0.002

WBC counts on POD3 ≥ 10,370 (/μl)

1.38

0.605–3.160

0.443

CRP on POD3 ≥ 13.4 (mg/dl)

3.25

1.38–7.68

0.007

b. IAI

DOV on POD1 ≥ 380 (ml)

0.602

0.328–1.110

0.102

DA on POD1 ≥ 608 (U/l)

3.59

1.77–7.290

 < 0.001

CRP on POD1 ≥ 8.58 (mg/dl)

1.77

1–3.13

0.048

DOV on POD3 ≥ 125 (ml)

0.609

0.338–1.1

0.099

DA on POD3 ≥ 96 (U/l)

1.38

0.692–2.73

0.363

WBC counts on POD3 ≥ 10,560 (/μl)

1.46

0.8330–2.55

0.187

CRP on POD3 ≥ 13.95 (mg/dl)

2.85

1.65–4.9

 < 0.001

c. CR-POPF

DOV on POD1 ≥ 227 (ml)

0.258

0.123–0.529

 < 0.001

DA on POD1 ≥ 2180 (U/l)

6.8

3.24–14.3

 < 0.0001

CRP on POD1 ≥ 7.82 (mg/dl)

2.04

0.822–5.06

0.124

DOV on POD3 ≥ 190 (ml)

1.32

0.646–2.71

0.443

DA on POD3 ≥ 103 (U/l)

3.56

1.4–9.09

0.008

WBC counts on POD3 ≥ 11,160 (/μl)

1.59

0.769–3.27

0.211

CRP on POD3 ≥ 13.94 (mg/dl)

3.41

1.68–6.95

 < 0.001

d. CR-CL

DOV on POD1 ≥ 390 (ml)

2.85

0.899–9.01

0.075

DOV on POD3 ≥ 332 (ml)

5.36

1.56–18.4

0.008

CRP on POD3 ≥ 13.07 (mg/dl)

0.361

0.0988–1.32

0.123

e. CR-PPH

DOV on POD1 ≥ 206 (ml)

0.432

0.186–1.00

0.051

DA on POD1 ≥ 457 (U/l)

1.25

0.29–5.43

0.763

DA on POD3 ≥ 55 (U/l)

6.01

0.59–61.2

0.13

WBC counts on POD3 ≥ 11,160 (/μl)

2

0.85–4.67

0.111

CRP on POD3 ≥ 13.55 (mg/dl)

11.6

2.61–51.6

0.001

  1. DOV drain output volume, DA drain amylase, WBC white blood cell, CRP c-reactive protein, POD postoperative day, IAI intraabdominal infection, CR clinically relevant, POPF postoperative pancreatic fistula, CL chyle leak, PPH post-pancreatectomy hemorrhage