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Table 3 Molecular immunohistochemical indexs

From: Analysis of risk factors and prognosis of 253 lymph node metastasis in colorectal cancer patients

  253 lymph node negative group (n = 381) 253 lymph node positive group (n = 10) P
Ki67 74.5% ± 15.6 % 79.0% ± 8.8 % 0.371
MSH2 79.4% ± 12.7 % 75.5 ± 11.7 0.340
MSH6 78.9% ± 13.1 % 68.0% ± 26.1 % 0.013
MLH1 72.5% ± 15.6 % 56.5% ± 24.3 % 0.002
PMS2 70.9% ± 17.8 % 60.0% ± 21.2 % 0.059
MMR    0.602
 DMMR 9 (2.7%) 0 (0.0%)  
 PMMR 330 (97.3%) 10 (100.0%)  
HER1    0.813
 Negative 42 (12.5%) 1 (10.0%)  
 Positive 294 (87.5%) 9 (90.0%)  
HER2    0.647
 Negative 89 (27.1%) 3 (30.0%)  
 + 157 (47.7%) 3 (30.0%)  
 ++ 81 (24.6%) 4 (40.0%)  
 +++ 2 (0.6%) 0 (0.0%)  
KRAS    0.965
 Wild type 72 (65.5%) 2 (66.7%)  
 Mutant type 38 (34.5%) 1 (33.3%)  
NRAS    0.678
 Wild type 104 (94.5%) 3 (100.0%)  
 Mutant type 6 (5.5%) 0 (0.0%)  
BRAF    0.869
 Wild type 110 (99.1%) 3 (100.0%)  
 Mutant type 1 (0.9%) 0 (0.0%)  
PIK3CA    0.813
 Wild type 107 (98.2%) 3 (100.0%)  
 Mutant type 2 (1.8%) 0 (0.0%)