Table 2 Univariate and multivariate analyses of prognostic factors for 5-year OS in patients with CRC

Gender

0.068

NS

Female

1

Male

0.411

0.158–1.070

Age

0.005

0.031

 < 65

1

1

 ≥ 65

3.686

1.468–9.251

3.089

1.111–8.585

Location

0.616

NS

Colon

1

Rectum

1.296

0.470–3.573

T stage

0.012

0.343

T1–T2

1

1

T3–T4

1.703

1.122–2.585

1.731

0.556–5.390

N stage

0.013

0.009

N0

1

1

N1–N2

3.274

1.282–8.359

4.401

1.456–13.304

M stage

0.001

0.010

M0

1

1

M1

6.016

2.398–15.094

4.575

1.441–14.522

Intestinal obstruction

0.005

0.123

No

1

1

Yes

3.686

1.468–9.251

2.668

0.766–9.294

CEA

0.125

NS

 < 5

1

 ≥ 5

2.211

0.802–6.095

CA19-9

0.616

NS

 < 37

1

 ≥ 37

1.706

0.569–5.111

CIP2A

0.192

NS

Low

1

High

1.816

0.740–4.456

NLR

0.012

0.519

 < 2.03

1

1

 ≥ 2.03

3.030

1.206–7.612

1.414

0.493–4.051

COCN

0.020

0.232

0

1

1

1 + 2

4.829

1.278–18.251

2.714

0.528–13.946