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Table 1 Tumor pathology and immunohistochemistry characteristics

From: Esophageal leiomyoma and simultaneous overlying squamous cell carcinoma: a case report and review of the literature

Tumor type

SCC, poorly differentiated (G3)

Residual tumor size

0.6 cm

Tumor extension

Tumor invaded submucosal (at least)

Proximal margin

Free of tumor

Distal margin

Free of tumor

Radial margin

Free of tumor

Treatment effect

Near complete response, score 1 (single cell and small groups of cancer cells

Lymphovascular invasion

Present

Perineural invasion

Present

Lymph-node invasion

Total: 5, involved: 2; metastatic poorly differentiated squamous cell carcinoma (LN2)

Additional pathologic findings

Multiple leiomyomas, the largest one measuring: 2 cm in diameter

Pathologic staging

ypT1bN1Mx

Immunohistochemistry

Negative for C-KIT and CDX2 proto-oncogenes

 

Positive for Desmin and P63 proto-oncogenes

Note

This staging categorizes the extent of tumor actually present at the time of examination (after the chemotherapy). The “y” categorization is not an estimate of tumor before chemotherapy