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Table 3 ROC analysis for the prediction of CRPF occurrence after LPD

From: Post-operative procalcitonin and C-reactive protein predict pancreatic fistula after laparoscopic pancreatoduodenectomy

Days

Variables

Cutoff

AUC (95%CI)

P value

Sensitivity

Specificity

POD1

WBC

12.44

0.576 (0.417–0.734)

0.317

68.8%

51.9%

 

PCT

0.65

0.788c (0.650–0.925)

 < 0.001

81.3%

75.9%

 

CRP

64.58

0.625 (0.467–0.783)

0.099

62.5%

68.4%

POD2

WBC

18.84

0.695a (0.541–0.849)

0.010

62.5%

72.6%

 

PCT

3.30

0.931c (0.875–0.987)

 < 0.001

81.3%

93.7%

 

CRP

216.93

0.794 (0.711–0.876)

 < 0.001

87.5%

71.5%

POD3

WBC

14.71

0.762a,b (0.647–0.877)

 < 0.001

70.6%

72.6%

 

PCT

2.10

0.951c (0.903–0.999)

 < 0.001

88.2%

92.9%

 

CRP

201.40

0.629 (0.495–0.762)

0.081

64.7%

64.3%

 

DFA

79.50

0.694 (0.555–0.833)

0.008

76.5%

70.2%

POD5

WBC

12.70

0.732a (0.600–0.863)

0.002

56.3%

81.6%

 

PCT

0.91

0.930c (0.887–0.972)

 < 0.001

93.8%

87.9%

 

CRP

95.01

0.702 (0.572–0.832)

0.008

81.3%

60.3%

POD7

WBC

10.90

0.776 (0.632–0.919)

0.001

85.7%

60.9%

 

PCT

0.455

0.905c (0.844–0.966)

 < 0.001

85.7%

86.2%

 

CRP

73.20

0.746 (0.631–0.861)

0.059

85.7%

64.5%

  1. There were significant differences in the AUC values obtained from the ROC curves for the aWBC counts and PCT levels, the bWBC counts and CRP levels, and the cPCT and CRP levels (P ˂ 0.05, Delong’s test). Bold font indicates significance at the reported analysis
  2. ROC receiver operating characteristic, AUC area under the curve, CRP C-reactive protein, WBC white blood cell, PCT procalcitonin, POD post-operative day, CRPF clinically relevant pancreatic fistula, LPD laparoscopic pancreaticoduodenectomy, DFA drain fluid amylase