Variable | Upstaging to invasive cancer (%) | Axillary lymph node metastasis (%) | ||||
---|---|---|---|---|---|---|
Present | Absent | p-value | Present | Absent | p-value | |
Size of DCIS, cm | 0.048 | 0.017 | ||||
≤ 2 | 27 (17.3) | 129 (82.7) | 1 (0.6) | 154 (99.4) | ||
> 2 and ≤ 5 | 22 (17.7) | 102 (82.3) | 1 (0.8) | 123 (99.2) | ||
> 5 | 10 (37.3) | 17 (63.0) | 2 (7.1) | 26 (92.9) | ||
Palpability | 0.177 | 0.215 | ||||
Non-palpable | 41 (17.5) | 193 (82.5) | 2 (0.9) | 232 (99.1) | ||
Palpable | 18 (24.7) | 55 (75.3) | 2 (2.7) | 71 (97.3) | ||
Mammographic calcification | 0.127 | 0.604 | ||||
Present | 17 (14.8) | 98 (85.2) | 3 (1.6) | 189 (98.4) | ||
Absent | 42 (21.9) | 150 (78.1) | 1 (0.9) | 114 (99.1) | ||
Ultrasonic mass-forming lesions | 0.001 | 0.135 | ||||
Present | 49 (24.7) | 149 (75.3) | 4 (2.0) | 194 (98.0) | ||
Absent | 10 (9.2) | 99 (90.8) | 0 (0.0) | 109 (100.0) | ||
Tumour location | 0.046 | 0.240 | ||||
Upper-outer | 19 (18.1) | 86 (81.9) | 3 (2.9) | 102 (97.1) | ||
Upper-inner | 13 (26.0) | 37 (74.0) | 0 (0.0) | 50 (100.0) | ||
Lower-outer | 14 (23.3) | 46 (76.7) | 0 (0.0) | 60 (100.0) | ||
Lower-inner | 5 (7.7) | 60 (92.3) | 0 (0.0) | 65 (100.0) | ||
Multicentric | 8 (29.6) | 19 (70.4) | 1 (3.7) | 26 (96.3) | ||
Biopsy method | < 0.001 | 0.212 | ||||
Core-needle | 53 (30.5) | 121 (69.5) | 4 (2.3) | 170 (97.7) | ||
V ABB | 1 (12.5) | 7 (87.5) | 0 (0.0) | 8 (100.0) | ||
E xcisional | 5 (4.0) | 120 (96.0) | 0 (0.0) | 125 (100.0) | ||
Breast surgery | 0.004 | 0.057 | ||||
BCS | 18 (12.4) | 127 (87.6) | 0 (0.0) | 145 (100.0) | ||
Mastectomy | 41 (25.3) | 121 (74.7) | 4 (2.5) | 158 (97.5) | ||
Comedo necrosis | 0.028 | 0.995 | ||||
Absent | 22 (14.3) | 132 (85.7) | 2 (1.3) | 152 (98.7) | ||
Present | 37 (24.2) | 116 (75.8) | 2 (1.3) | 151 (98.7) | ||
Nuclear grade | 0.021 | 0.478 | ||||
Low | 6 (9.0) | 61 (91.0) | 0 (0.0) | 67 (100.0) | ||
Intermediate | 29 (19.3) | 121 (80.7) | 2 (1.3) | 148 (98.7) | ||
High | 24 (26.7) | 66 (73.3) | 2 (2.2) | 88 (97.8) | ||
ER | 0.003 | 0.864 | ||||
Positive | 38 (15.8) | 203 (84.2) | 3 (1.2) | 238 (98.8) | ||
Negative | 21 (31.8) | 45 (68.2) | 1 (1.5) | 65 (98.5) | ||
PR | < 0.001 | 0.416 | ||||
Positive | 28 (13.3) | 183 (86.7) | 2 (0.9) | 209 (99.1) | ||
Negative | 31 (32.3) | 65 (67.7) | 2 (2.1) | 94 (97.9) | ||
HER2 neu | 0.201 | 0.966 | ||||
Negative | 41 (17.6) | 192 (82.4) | 3 (1.3) | 230 (98.7) | ||
Positive | 18 (24.3) | 56 (75.7) | 1 (1.4) | 73 (98.6) | ||
Ki-67 | 0.010 | 0.714 | ||||
Low | 26 (14.4) | 155 (85.6) | 2 (1.1) | 179 (98.9) | ||
High | 33 (26.2) | 93 (73.8) | 2 (1.6) | 124 (98.4) | ||
Type of DCIS | 0.027 | 0.748 | ||||
Cribriform | 18 (14.4) | 107 (85.6) | 2 (1.6) | 123 (98.4) | ||
Solid | 4 (10.8) | 33 (89.2) | 2 (1.4) | 143 (98.6) | ||
Comedo | 37 (25.5) | 108 (74.5) | 0 (0.0) | 37 (100.0) | ||
Total | 59 (19.2) | 248 (80.8) | 4 (1.3) | 303 (98.7) |