Table 1 Demographic and clinicopathologic characteristics of the 101 patients (with or without PAD) after SPKT
Variables | Patients without PAD (n = 84) | Patients with PAD (n = 17) | p-value |
|---|---|---|---|
Recipient age, years | 42.7 ± 9.2 | 44.6 ± 7.2 | 0.416 |
Recipient sex | 0.308 | ||
Male | 43 (51.2%) | 11 (64.7%) | |
Female | 41 (48.8%) | 6 (35.3%) | |
Recipient BMI (kg/m2) | 24.9 ± 4.3 | 25.8 ± 3.6 | 0.425 |
Duration of diabetes mellitus, years | 26.3 ± 8.9 | 28.6 ± 6.9 | 0.330 |
Donor age, years | 23.8 ± 11.7 | 27 ± 11.4 | 0.323 |
Donor BMI (kg/m2) | 22.4 ± 3.1 | 25.4 ± 3.5 | 0.126 |
Donor sex | 0.256 | ||
Male | 52 (61.9%) | 8 (47.1%) | |
Female | 32 (38.1%) | 9 (52.9%) | |
Pre-transplantation dialysis duration, months | 31.0 ± 24.1 | 36.4 ± 24.5 | 0.480 |
Pre-emptive transplantation | 0.432 | ||
Yes | 17 (20%) | 5 (30%) | |
No | 67 (80%) | 12 (70%) | |
Systolic blood pressure, mmHg | 138 ± 17 | 147 ± 18 | 0.830 |
Diastolic blood pressure, mmHg | 80 ± 9 | 85 ± 10 | 0.04 |
HbA1c pre-transplantation, % | 7.8 ± 1.9 | 7.6 ± 1.1 | 0.657 |
Total cholesterol, μmol/l | 5.3 ± 1.4 | 5.1 ± 1.1 | 0.626 |
Triglycerides, μmol/l | 1.9 ± 1.2 | 1.9 ± 0.8 | 0.837 |
Limb ischemia, gangrene, amputation | 0.03 | ||
Yes | 3 (4%) | 4 (23%) | |
No | 81 (96%) | 13 (77%) | |
CVA/TIA | 0.89 | ||
Yes | 4 (5%) | 1 (6%) | |
No | 80 (95%) | 16 (94%) | |
Coronary heart disease | 0.02 | ||
Yes | 21 (25%) | 9 (53%) | |
No | 63 (75%) | 8 (47%) | |
Hypertension before transplantation | 0.283 | ||
Yes | 74 (83%) | 13 (77%) | |
No | 10 (17%) | 4 (23%) | |
Antihypertensive drugs | 0.876 | ||
Assumed (n) | 2.6 ± 1.3 | 2.4 ± 1.5 | |
Ever smoker | 0.535 | ||
Yes | 28 (33.3%) | 7(41%) | |
No | 56 (66.7%) | 10 (59%) | |
Immunosuppression induction therapy | 0.831 | ||
ALG/ATG | 62 (73.8%) | 12 (70.6%) | |
IL2-RA | 15 (17.9%) | 4 (23.5%) | |
None | 7 (8.3%) | 1 (5.9%) | |
CNI | 0.359 | ||
Tacrolimus | 80 (92.5%) | 17 (100%) | |
Ciclosporin | 4 (4.8%) | 0 | |
AP drug | 0.318 | ||
MMF | 66 (78.6%) | 16 (94.1%) | |
SRL | 14 (16.7%) | 1 (5.9%) | |
Multiple | 3 (3.6%) | 0 | |
None | 1 (1.2%) | 0 | |
Steroid-free after 1 year | 55 (65%) | 10 (59%) | 0.61 |