Table 1 Clinical parameters, management and prognosis of reported cases with adenosquamous carcinoma of the ampulla of Vater
Year | Author | Age | Gender | Symptom | Examination | Size (mm) | Preoperative biopsy | Operative method | LN metastasis | Postoperative radiation or chemotherapy | Stage | Prognosis (months) | Postoperative distant metastasis | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2002 | Ueno et al.[10] | 47 | M | Jaundice, fatigue | ERCP, duodenoscopy | 22 | SCC | PD | (−) | ND | IV | 10 Dead | ( +) |
2 | 2005 | Ri et al.[11] | 62 | F | Jaundice, fatigue, abdominal pain | Contrast-enhanced CT, duodenoscopy, ERCP | 15 | ND | PPPD | (−) | ( +) | II | 11 Dead | ( +) |
3 | 2013 | Yang et al.[3] | 64 | M | Jaundice, abdominal pain | Contrast-enhanced CT, ERCP | 34 | ADC | PD | ( +) | ( +) | IIB | 6 Dead | ( +) |
4 | 2013 | Yang et al.[3] | 82 | M | Jaundice | NM | NM | ND | Ampullectomy | (−) | ND | IB | 14 Dead | ( +) |
5 | 2013 | Yang et al.[3] | 68 | M | Jaundice, abdominal pain | NM | NM | SCC | PD | ( +) | NM | III | 7 Dead | ( +) |
6 | 2013 | Yang et al.[3] | 34 | F | Jaundice, abdominal pain | NM | NM | SCC | PD | (−) | NM | III | 10 Dead | ( +) |
7 | 2013 | Yang et al.[3] | 77 | M | Jaundice, abdominal pain | NM | NM | SCC | PD | (−) | NM | IIB | 6 Dead | ( +) |
8 | 2014 | Kshirsagar et al. [2] | 58 | M | Jaundice, abdominal pain, vomiting | Contrast-enhanced CT, ERCP | 40 | SCC | ERCP guided stent | (−) | ND | NM | NM | NM |
9 | 2015 | Hoshimoto et al. [9] | 81 | F | No symptoms | Contrast-enhanced CT, MRCP, endoscopic ultrasonography, duodenoscopy, ERCP | 11 | ADC + SCC | PPPD | (−) | ND | IA | 20 Alive | (-) |
10 | 2018 | Carvalho et al.[12] | 68 | M | Jaundice, choluria, acholia | Endoscopic ultrasonography | NM | ADC | PD | ( +) | ND | IIIA | 10 Alive | (-) |
11 | 2018 | Milanetto et al.[13] | 81 | F | Jaundice, pruritus, hyperchromic urine, acholic stool | Contrast-enhanced CT, abdominal ultrasonography | 40 | ND | PPPD | ( +) | ND | NM | 16 Dead | ( +) |
12 | 2019 | Kun Wang et al. [14] | 60 | M | Jaundice, fatigue, hyperchromic urine | Contrast-enhanced CT | 25 | ND | PD | (−) | ND | IIA | 8 Alive | (-) |
13 | 2014 | Xue Wen et al. [15] | 59 | F | Jaundice, abdominal pain | NM | 46 | ND | PD | ( +) | ND | III | 7 Dead | NM |
14 | 2014 | Xue Wen et al. [15] | 59 | F | Jaundice | NM | 35 | ND | PD | ( +) | ( +) | III | 11 Dead | NM |
15 | 2014 | Xue Wen et al. [15] | 67 | M | Jaundice, abdominal distension | NM | 22 | ND | PD | ( +) | ND | II | 2 Dead | NM |
16 | 2014 | Xue Wen et al. [15] | 54 | M | Jaundice | NM | 15 | ND | PD | (−) | ND | I | 10 Dead | NM |
17 | 2014 | Xue Wen et al. [15] | 66 | M | Jaundice, abdominal pain | NM | 27 | ND | PD | (−) | ND | III | 8 Dead | NM |
18 | Present case | 67 | F | Jaundice, pruritus, hyperchromic urine, acholic stool, vomiting | Contrast-enhanced CT, MRCP, ERCP, PET/CT | 36 | ADC | laparoscopic radical gastrectomy + PD | (−) | ND | IB | 6 Alive | (-) |