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Table 4 Separate results of included study groups

From: Damage control strategy in perforated diverticulitis with generalized peritonitis

Variable SG 1 SG 2 SG 3 SG 4 SG 5
Multiple publication Yes Yes No No No
2010 2016
2012 2018
2018
Population Perforated diverticulitis of the left colon with generalized peritonitis Perforated diverticulitis of the left colon with generalized peritonitis Perforated diverticulitis of the left colon with generalized peritonitis Perforated diverticulitis of the left colon with generalized peritonitis Perforated diverticulitis of the left colon with generalized peritonitis
Intervention DCS DCS ABTheraTM DCS DCS
Comparator 2010: PRA, HP
2012: no
2016: PRA, HP
2018: No
2018:No
SuprasorbVR No No
Main outcome 2010: not specified 2016: Not specified Not specified
Comment
Comparision of different systems for vacuum therapy in DCS patients
Mortality,
Morbidity,
Rate of intestinal anastomoses at 2nd look surgery
Not specified
2012: not specified 2018: Stoma rate at discharge  
2018: Prognostic impact of ongoing peritonitis at 2nd look surgery
Design POS RS RS RS RS
Follow-up Length not specified Length not specified No 47 month (mean) No
n 51 74 67 34 30
ASA > 2, n (%) 51 (100) 58 (78) 48 (72) 22 (65) 30 (100)
Age 69 (28–87) (median) 67 (30–92) (median) 67 (43–86) (median) 66.9 (mean) 68.5 (35–84) (median)
Female:male (%) 55:45 54:46 78:22 56:44 60:40
Sepsis/septic shock, n (%) 16 (31) 16 (22) 34 (51) 34 (100) 8 (27)
Hinchey III, n (%) 40 (78) 60 (81) 41 (61) 13 (38) 17 (57)
Hinchey IV, n (%) 11 (22) 14 (19) 18 (27) 21 (62) 13 (43)
MPI median 26 (12–39) 22.4 (6–42) 22 (0–39) 25.12 26.2 (12–40)
MPI ≥ 26, n (%) 32 (63) 29 (39) 24 (36) 23 (68) 18 (60)
Colorectal anastomosis at 2nd look operation, n (%) 38 of 50 (74) 62 (84) 37 of 65 (57) 24 (71) 24 (80)
Diverting Ileostomy at 2nd look, n (%) 4 of 50 (8) 25 (34) 6 of 65 (9) 3 (9) 0 (0)
End colostomy at 2nd look, n (%) 12 of 50 (24) 12 (16) 28 of 65 (43) 10 (29) 6 (20)
Peritonitis remission at 2nd look, n (%) 28 of 50 (56) 41 (55) 46 of 65 (71) 27 (79) 24 (80)
Fascia closure at 2nd look, n (%) 50 of 50 (100) 74 (100) 46 of 65 (71) 34 (100) 30 (100)
Surgical Morbidity, n (%) 19 (37) 26 (35) 14 (21) 14 (41) 7 (23)
Anastomotic leak (AL), n (%) 5 of 38 (13) 8 of 62 (13) 9 of 37 (24) 1 of 24 (4) 1 of 24 (4)
Revision laparotomy, n (%) 4 (8) 11 (15)* 19 (28) 3 (9) 0 (0)
Fascia dehisience, n (%) 1 of 50 (2) 5 (7) 5 of 65 (7) 2 (6) 0 (0)
Mortality (30 d), n (%) 5 (10) 5 (7) 9 (13) 4 (12) 1 (3)
Stomarate at discharge, n (%) 16 of 50 (32) 43 (58) 34 of 65 (52) 14 (41)** 6 (20)
  1. SG 1: Perathoner/Kafka-Ritsch et al., University Hospital Innsbruck, Austria; SG 2: Sohn et al., DCS Study Group Munich/Berlin, Germany; SG 3: Gasser et al., University Hospitals Innsbruck/Salzburg, Austria; SG 4: Tartaglia et al., New Santa Chiara Hospital, University of Pisa, Italy; SG 5: Brillantino et al., “A Cardarelli” Hospital, Naples, Italy
  2. HP  Hartmann’s procedure, PRA  primary anastomosis, RS retrospective, POS  prospective observational study, DCS  damage control surgery
  3. *At revision laparotomy three patients received additional loop ileostomy and three other patients received end colostomy for anastomotic complication
  4. **At revision laparotomy, one patient received end colostomy