Table 4 Separate results of included study groups
From: Damage control strategy in perforated diverticulitis with generalized peritonitis
Variable | SG 1 | SG 2 | SG 3 | SG 4 | SG 5 |
|---|---|---|---|---|---|
Multiple publication | Yes | Yes | No | No | No |
2010 | 2016 | ||||
2012 | 2018 | ||||
2018 | |||||
Population | Perforated diverticulitis of the left colon with generalized peritonitis | Perforated diverticulitis of the left colon with generalized peritonitis | Perforated diverticulitis of the left colon with generalized peritonitis | Perforated diverticulitis of the left colon with generalized peritonitis | Perforated diverticulitis of the left colon with generalized peritonitis |
Intervention | DCS | DCS | ABTheraTM | DCS | DCS |
Comparator | 2010: PRA, HP 2012: no | 2016: PRA, HP 2018: No 2018:No | SuprasorbVR | No | No |
Main outcome | 2010: not specified | 2016: Not specified | Not specified Comment Comparision of different systems for vacuum therapy in DCS patients | Mortality, Morbidity, Rate of intestinal anastomoses at 2nd look surgery | Not specified |
2012: not specified | 2018: Stoma rate at discharge | ||||
2018: Prognostic impact of ongoing peritonitis at 2nd look surgery | |||||
Design | POS | RS | RS | RS | RS |
Follow-up | Length not specified | Length not specified | No | 47 month (mean) | No |
n | 51 | 74 | 67 | 34 | 30 |
ASA > 2, n (%) | 51 (100) | 58 (78) | 48 (72) | 22 (65) | 30 (100) |
Age | 69 (28–87) (median) | 67 (30–92) (median) | 67 (43–86) (median) | 66.9 (mean) | 68.5 (35–84) (median) |
Female:male (%) | 55:45 | 54:46 | 78:22 | 56:44 | 60:40 |
Sepsis/septic shock, n (%) | 16 (31) | 16 (22) | 34 (51) | 34 (100) | 8 (27) |
Hinchey III, n (%) | 40 (78) | 60 (81) | 41 (61) | 13 (38) | 17 (57) |
Hinchey IV, n (%) | 11 (22) | 14 (19) | 18 (27) | 21 (62) | 13 (43) |
MPI median | 26 (12–39) | 22.4 (6–42) | 22 (0–39) | 25.12 | 26.2 (12–40) |
MPI ≥ 26, n (%) | 32 (63) | 29 (39) | 24 (36) | 23 (68) | 18 (60) |
Colorectal anastomosis at 2nd look operation, n (%) | 38 of 50 (74) | 62 (84) | 37 of 65 (57) | 24 (71) | 24 (80) |
Diverting Ileostomy at 2nd look, n (%) | 4 of 50 (8) | 25 (34) | 6 of 65 (9) | 3 (9) | 0 (0) |
End colostomy at 2nd look, n (%) | 12 of 50 (24) | 12 (16) | 28 of 65 (43) | 10 (29) | 6 (20) |
Peritonitis remission at 2nd look, n (%) | 28 of 50 (56) | 41 (55) | 46 of 65 (71) | 27 (79) | 24 (80) |
Fascia closure at 2nd look, n (%) | 50 of 50 (100) | 74 (100) | 46 of 65 (71) | 34 (100) | 30 (100) |
Surgical Morbidity, n (%) | 19 (37) | 26 (35) | 14 (21) | 14 (41) | 7 (23) |
Anastomotic leak (AL), n (%) | 5 of 38 (13) | 8 of 62 (13) | 9 of 37 (24) | 1 of 24 (4) | 1 of 24 (4) |
Revision laparotomy, n (%) | 4 (8) | 11 (15)* | 19 (28) | 3 (9) | 0 (0) |
Fascia dehisience, n (%) | 1 of 50 (2) | 5 (7) | 5 of 65 (7) | 2 (6) | 0 (0) |
Mortality (30 d), n (%) | 5 (10) | 5 (7) | 9 (13) | 4 (12) | 1 (3) |
Stomarate at discharge, n (%) | 16 of 50 (32) | 43 (58) | 34 of 65 (52) | 14 (41)** | 6 (20) |