Table 2 Prognostic factors for OS for ICC patients in univariate analysis

Age ≥ 60 years

0.778 (0.483–1.251)

0.300

Preoperative CEA > 5 ng/mL

2.365 (1.429–3.913)

0.001

Male

1.418 (0.887–2.267)

0.144

RDW-SD > 40.2 fl

0.503 (0.314–0.806)

0.004

BMI ≥ 24 kg/m²

1.356 (0.843–2.182)

0.209

RDW-CV > 12.6%

0.581(0.356–0.949)

0.030

ASA score 3–4

0.970 (0.420–2.238)

0.943

ALB ≥ 40 g/L

0.600 (0.361–0.996)

0.048

Cirrhosis

0.929 (0.575–1.500)

0.763

TBIL > 21 umol/L

0.913 (0.438–1.904)

0.808

HBsAg ( +)

0.754 (0.420–1.351)

0.343

AST > 40 U/L

1.773 (0.909–3.458)

0.093

T3-T4 stage

2.381 (.431–3.962)

0.001

ALT > 50U/L

1.814 (0.899–3.660)

0.096

Lymphnode metastasis

 < 0.001

Operation time ≥ 230 min^b

1.785(1.118–2.851)

0.015

Undissected lymph node

Reference

–

Blood loss ≥ 300 ml^b

1.713 (1.053–2.788)

0.030

Negative lymph node

0.742 (0.414–1.331)

0.317

Major liver resection

1.419 (0.832–2.419)

0.198

Positive lymph node

2.808(1.554–5.072)

0.001

Post-operative complications

1.027 (0.640–1.647)

0.913

Tumor size ≥ 5 cm

1.529 (0.956–2.448)

0.077

Preoperative therapy

0.648 (0.204–2.060)

0.462

Multiple tumors

1.657(0.955–2.874)

0.073

Adjuvant therapy

0.663 (0.410–1.072)

0.094

Tumor location (central tumor)

0.587 (0.366–0.941)

0.027

The prognostic value on SCC score

0.007

Tumor location (right lobe)

0.858 (0.588–1.252)

0.427

SCC = 0

Reference

–

Poor differentiation

1.667 (1.013–2.743)

0.044

SCC = 1

0.554 (0.320–0.961)

0.035

Preoperative CA19-9 > 27 U/mL

1.332 (0.763–2.327)

0.313

SCC = 2

0.411 (0.231–0.730)

0.002