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Table 5 Univariable and multivariable analysis of risk factors for clinically relevant postoperative pancreatic fistula in high-risk of pancreatic fistula patients

From: The prognostic value of external vs internal pancreatic duct stents after pancreaticoduodenectomy in patients with FRS ≥ 4: a retrospective cohort study

 

Univariable analysis

Multivariable analysis

 

OR

95%CI

P-value

OR

95%CI

P-value

Age (years)

1.000

0.969–1.032

0.999

   

Female (ref: male)

0.976

0.502–1.896

0.942

   

BMI (kg/m2)

1.167

1.040–1.311

0.009

1.175

1.034–1.335

0.013

Hypertension

2.490

1.257–4.932

0.009

1.791

0.838–3.829

0.133

Diabetes

2.234

0.871–5.728

0.094

   

Smoke

0.718

0.366–1.406

0.334

   

Drink

0.663

0.312–1.409

0.285

   

Weight Loss

1.262

0.847–1.880

0.253

   

Preoperative biliary drainage

1.354

0.645–2.843

0.423

   

Preoperative total bilirubin (μmol/L) (ref: ≤ 21)

1.415

0.738–2.715

0.296

   

Preoperative direct bilirubin (μmol/L) (ref: ≤ 8)

1.613

0.848–3.069

0.145

   

Preoperative CA 199 (U/mL) (ref: ≤ 37)

0.791

0.416–1.506

0.476

   

Operative time (min)

0.999

0.997–1.002

0.463

   

Intraoperative bleeding (mL)

1.000

0.999–1.001

0.815

   

Vascular resection

0.583

0.154–2.208

0.427

   

Internal stent (ref: external stent)

2.680

1.149–6.247

0.022

3.376

1.318–8.646

0.011

Blood transfusion

2.214

1.134–4.319

0.020

2.777

1.310–5.887

0.008

Texture Firm (ref: soft)

0.276

0.033–2.295

0.233

   

Pancreatic duct diameter (cm)

0.003

0.000–0.319

0.014

0.003

0.000–0.456

0.024

Pancreatic adenocarcinoma or pancreatitis (ref: ampullary, duodenal, cystic, islet cell, etc.)

1.480

0.636–3.440

0.363

   
  1. The italic values reflected that there was a significant difference between the two groups