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Table 3 Baseline characteristics and pathological outcomes in elderly patients: PSM analysis

From: Short-term outcomes after minimally invasive versus open pancreaticoduodenectomy in elderly patients: a propensity score-matched analysis

Variables Original cohort P-value Matched cohort P-value
MIPD (N = 20) OPD (N = 66) MIPD (N = 17) OPD(N = 34)
Age (years) 74.5 ± 6.77 72.48 ± 5.35 0.234 73.76 ± 5.68 73.70 ± 6.82 0.974
Male (Male) 14 (70.0%) 40 (60.6%) 0.313 13 (76.5%) 25 (73.5%) 0.553
Malignancy (n, %) 19 (95%) 59 (84.9%) 0.402 16 (94.1%) 32 (94.1%) > 0.999
CCI (n, %)    0.211    0.558
 0 6 (30.0%) 28 (42.4%)   6 (35.3%) 12 (35.3%)  
 1 6 (30.0%) 22 (33.3%)   6 (35.3%) 12 (35.3%)  
 2 7 (35.0%) 12 (18.2%)   4 (23.5%) 8 (23.5%)  
 3 0 (0%) 3 (4.5%)   0 (0%) 2 (5.9%)  
 4 0 (0%) 1 (1.5%)   0 (0%) 0 (0%)  
 5 1 (5.0%) 0 (0%)   1 (5.9%) 0 (0%)  
ASA (n, %)    0.388    0.463
 I 0 (0%) 0 (0%)   0 (0%) 0 (0%)  
 II 5 (25.0%) 21 (31.8%)   4 (23.5%) 10 (29.4%)  
 III 15 (75.0%) 45 (68.2%)   13 (76.5%) 24 (70.6%)  
Tumor type (n, %)    0.402    0.583
 Benign 1 (5.0%) 6 (9.1%)   1 (3.8%) 2 (5.9%)  
 Ampullary cancer 9 (45.0%) 16 (24.2%)   7 (41.2%) 10 (29.4%)  
 CBD cancer 4 (20.0%) 11 (16.7%)   3 (17.6%) 8 (23.5%)  
 PDAC 5 (25.0%) 26 (39.4%)   5 (29.4%) 12 (35.3%)  
 IPMN 0 (0%) 3 (4.5%)   0 (0%) 2 (5.9%)  
 PNET 0 (0%) 3 (4.5%)   0 (0%) 0 (0%)  
 Duodenal cancer 1 (5.0%) 1 (1.5%)   1 (5.9%) 0 (0%)  
ECOG (n, %)    0.008    0.042
 0 13 (65.0%) 61 (92.4%)   12 (70.6%) 32 (94.1%)  
 1 5 (25.0%) 4 (6.1%)   3 (17.6%) 2 (5.9%)  
 2 2 (10%) 1 (1.5%)   2 (11.8%) 0 (0%)  
Tumor size (cm ± SD) 2.98 ± 1.93 3.26 ± 1.49 0.562 2.8. ± 2.0 2.92 ± 1.25 0.844
Lymph node harvest (number ± SD) 15.35 ± 8.26 19.42 ± 9.88 0.075 16.94 ± 8.56 17.44 ± 7.77 0.840
Pre-op bile drain (n, %) 8 (66.7%) 39 (59.1%) 0.696 10 (58.8%) 21(61.8%) 0.537
Abdominal surgery history (n, %) 4 (20.0%) 13 (19.7%) 0.601 3 (17.6%) 8 (23.5%) 0.462
  1. Italic indicate statistic significance
  2. PSM propensity score matching, MIPD minimal invasive pancreatoduodenectomy, OPD open pancreatoduodenectomy, CCI Charlson comorbidity index, ASA score American Society of Anesthesiologists classification score, ECOG Eastern Cooperative Oncology Group