Appraisal of long-time outcomes after curative surgery in elderly patients with gastric cancer: a propensity score matching analysis

Table 5 Univariate and multivariate analyses of prognostic factors for disease-specific survival in patients with stage III disease

	Univariate analysis			Mutivariate analysis
	Hazard ratio	95% CI	P value	Hazard ratio	95% CI	P value
Age (≧75vs < 75)	3.200	1.377–7.437	0.007	1.754	0.670–4.594	0.252
Gender (Female vs Male)	0.728	0.268–1.978	0.534
mFI (≧0.91 vs < 0.91)	1.296	0.573–2.930	0.534
CCI (Moderate/severe vs Low)	1.017	0.453–2.282	0.967
Lymphatic invasion (3 vs 0,1,2)	3.608	1.584–8.214	0.002	4.356	1.695–11.196	0.002
Venous invasion (2,3 vs 0,1)	1.241	0.555–2.773	0.599
pT(4 vs 1,2,3)	2.229	0.992–5.010	0.052
pN (2,3 vs 0,1)	1.683	0.741–3.820	0.213
The number of positive lymph node (≥5 vs < 5)	3.517	1.045–11.832	0.042	2.429	0.688–8.567	0.168
Histologic type (Differenciated vs Undifferenciated	0.448	0.177–1.134	0.090
Approach (Laparo vs Open)	1.513	0.625–3.662	0.359
Type of gastrectomy (TG vs DG/PG)	1.525	0.674–3.450	0.311
Lymphadectomy (≥D2 vs < D2)	0.501	0.221–1.136	0.098
Adjuvant chemotherapy (Present vs Absent)	0.469	0.211–0.963	0.049	0.682	0.271–1.512	0.402
Postoperative complication (CD3 ≥vs < 3)	1.984	0.589–6.689	0.269
CAR (≥0.064 vs < 0.064)	0.577	0.229–1.458	0.245
NLR (≥2.273 vs < 2.273)	1.186	0.526–2.675	0.681
PNI (≥49.8 vs < 49.8)	2.760	1.217–8.522	0.046	3.321	1.116–10.856	0.047

CD Clavien–Dindo, CI confidence interval, DG distal gastrectomy, EP elderly patient, NEP non-elderly patient, PG proximal gastrectomy, pT pathological depth of invasion, pN pathological lymph node metastasis, TG total gastrectomy

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