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Table 5 Univariate and multivariate analyses of prognostic factors for disease-specific survival in patients with stage III disease

From: Appraisal of long-time outcomes after curative surgery in elderly patients with gastric cancer: a propensity score matching analysis

  Univariate analysis Mutivariate analysis
Hazard ratio 95% CI P value Hazard ratio 95% CI P value
Age (75vs < 75) 3.200 1.377–7.437 0.007 1.754 0.670–4.594 0.252
Gender (Female vs Male) 0.728 0.268–1.978 0.534    
mFI (0.91 vs < 0.91) 1.296 0.573–2.930 0.534    
CCI (Moderate/severe vs Low) 1.017 0.453–2.282 0.967    
Lymphatic invasion (3 vs 0,1,2) 3.608 1.584–8.214 0.002 4.356 1.695–11.196 0.002
Venous invasion (2,3 vs 0,1) 1.241 0.555–2.773 0.599    
pT(4 vs 1,2,3) 2.229 0.992–5.010 0.052    
pN (2,3 vs 0,1) 1.683 0.741–3.820 0.213    
The number of positive lymph node (≥5 vs < 5) 3.517 1.045–11.832 0.042 2.429 0.688–8.567 0.168
Histologic type (Differenciated vs Undifferenciated 0.448 0.177–1.134 0.090    
Approach (Laparo vs Open) 1.513 0.625–3.662 0.359    
Type of gastrectomy (TG vs DG/PG) 1.525 0.674–3.450 0.311    
Lymphadectomy (≥D2 vs < D2) 0.501 0.221–1.136 0.098    
Adjuvant chemotherapy (Present vs Absent) 0.469 0.211–0.963 0.049 0.682 0.271–1.512 0.402
Postoperative complication (CD3 ≥vs < 3) 1.984 0.589–6.689 0.269    
CAR (≥0.064 vs < 0.064) 0.577 0.229–1.458 0.245    
NLR (≥2.273 vs < 2.273) 1.186 0.526–2.675 0.681    
PNI (≥49.8 vs < 49.8) 2.760 1.217–8.522 0.046 3.321 1.116–10.856 0.047
  1. CD Clavien–Dindo, CI confidence interval, DG distal gastrectomy, EP elderly patient, NEP non-elderly patient, PG proximal gastrectomy, pT pathological depth of invasion, pN pathological lymph node metastasis, TG total gastrectomy