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Table 1 Clinicopathological features of patients in the EP group and NEP group before and after propensity score matching

From: Appraisal of long-time outcomes after curative surgery in elderly patients with gastric cancer: a propensity score matching analysis

Characteristics

Before matching

After matching

EP group (n = 186)

NEP group (n = 440)

p value

EP group (n = 178)

NEP group (n = 175)

p value

Age (years)

80.0 ± 4.1

62.6 ± 9.5

 < 0.001

80.2 ± 4.0

63.8 ± 9.0

 < 0.001

Sex

  

0.206

  

0.473

 Male

127 (68.3)

323 (73.4)

 

123 (69.1)

127 (72.6)

 

 Female

59 (31.7)

117 (26.6)

 

55 (30.9)

48 (27.4)

 

CCI

  

 < 0.001

  

0.002

 Low

65 (34.9)

243 (55.2)

 

64 (36.0)

91 (52.0)

 

 Moderate/severe

121 (65.1)

197 (44.8)

 

114 (64.0)

84 (48.0)

 

 mFI

0.074 ± 0.068

0.046 ± 0.061

 < 0.001

0.073 ± 0.067

0.050 ± 0.064

 < 0.001

Number of analyzed lymph nodes

  

0.577

   

  < 16

8 (4.3)

21 (4.7)

 

0

0

 

 ≥16

178 (95.7)

419 (95.3)

 

178

175

 

 Number of positive lymph nodes

1.75 ± 5.34

1.62 ± 5.90

0.546

1.70 ± 4.80

2.13 ± 8.04

0.738

 Tumor size (mm)

40.4 ± 25.9

38.9 ± 25.6

0.470

40.5 ± 25.5

41.3 ± 26.3

 

Depth of tumor invasion

  

0.479

  

0.956

 T1

115 (61.8)

288 (65.5)

 

107 (60.1)

108 (61.7)

 

 T2

26 (14.0)

49 (11.1)

 

26 (14.6)

22 (12.6)

 

 T3

33 (17.7)

84 (19.1)

 

33 (18.5)

34 (19.4)

 

 T4

12 (6.5)

19 (4.3)

 

12 (6.8)

11 (6.3)

 

Lymph node metastasis

  

0.765

  

0.700

 Positive

51 (27.4)

112 (25.5)

 

49 (27.5)

46 (26.3)

 

 Negative

135 (72.6)

328 (74.5)

 

129 (72.5)

129 (73.7)

 

Histologic type

  

0.005

  

0.511

 Differentiated

116 (62.4)

220 (50.0)

 

111 (62.4)

115 (65.7)

 

 Undifferenciated

70 (37.6)

220 (50.0)

 

67 (37.6)

60 (34.3)

 

Lymphatic invasion

  

0.136

  

0.845

 Positive

110 (59.1)

231 (52.5)

 

106 (59.6)

106 (60.6)

 

 Negative

76 (40.9)

209 (47.5)

 

72 (40.4)

69 (39.4)

 

Venous invasion

  

0.004

  

0.973

 Positive

102 (54.8)

184 (41.8)

 

100 (56.2)

98 (56.0)

 

 Negative

84 (45.2)

256 (58.2)

 

78 (43.8)

77 (44.0)

 

Stage of disease

  

0.550

  

0.578

 I

124 (66.7)

308 (70.0)

 

116 (65.2)

119 (68.0)

 

 II

39 (21.0)

76 (17.2)

 

39 (21.9)

31 (17.7)

 

 III

23 (11.3)

56 (12.8)

 

23 (12.9)

25 (14.3)

 

Type of gastrectomy

  

0.508

  

0.951

 Distal

131 (70.4)

325 (73.9)

 

125 (70.2)

125 (71.4)

 

 Total

34 (18.3)

64 (14.5)

 

34 (19.1)

33 (18.9)

 

 Proximal

21 (11.3)

51 (11.6)

 

19 10.7)

17 (9.7)

 

Approach

  

0.476

  

0.101

 Open

71 (38.2)

183 (41.6)

 

67 (37.6)

82 (46.9)

 

 Laparo

115 (61.8)

257 (58.4)

 

111 (62.4)

93 (53.1)

 

Lymphadectomy

  

0.005

  

0.006

  < D2

136 (73.1)

293 (66.6)

 

130 (73.0)

103 (58.9)

 

 D2

50 (26.9)

147 (33.4)

 

48 (27.0)

72 (41.1)

 

Adjuvant chemotherapy

  

 < 0.001

  

 < 0.001

 Present

12 (6.5)

84 (19.1)

 

11 (6.2)

37 (21.1)

 

 Absent

174 (93.5)

356 (80.9)

 

167 (93.8)

138 (78.9)

 

Death from another disease

  

 < 0.001

  

0.022

 Present

33 (17.7)

37 (8.4)

 

31 (17.4)

16 (9.1)

 

 Absent

153 (82.3)

403 (91.6)

 

147 (82.6)

159 (90.9)

 

Death from primary disease

  

0.189

  

0.342

 Present

23 (12.4)

39 (8.9)

 

23 (12.9)

17 (9.7)

 

 Absent

163 (87.6)

401 (91.1)

 

155 (87.1)

158 (90.3)

 

CAR

0.127 ± 0.342

0.066 ± 0.176

 < 0.001

0.121 ± 0.340

0.066 ± 0.164

0.005

NLR

2.797 ± 1.677

2.464 ± 1.597

0.002

2.778 ± 1.647

2.366 ± 1.159

0.013

PLR

167.1 ± 87.7

160.3 ± 85.3

0.327

168.2 ± 87.9

152.4 ± 66.5

0.114

PNI

46.4 ± 5.8

50.4 ± 5.6

 < 0.001

46.5 ± 5.8

50.1 ± 5.1

 < 0.001

  1. Data are presented as the mean ± standard deviation or number (percentage) of patients
  2. CAR C-reactive protein-to-albumin ratio, CCI Charlson comorbidity index, EP elderly patient, mFI modified frailty index, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, PNI prognostic nutritional index, NEP non-elderly patient