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Table 1 Clinicopathological features of patients in the EP group and NEP group before and after propensity score matching

From: Appraisal of long-time outcomes after curative surgery in elderly patients with gastric cancer: a propensity score matching analysis

Characteristics Before matching After matching
EP group (n = 186) NEP group (n = 440) p value EP group (n = 178) NEP group (n = 175) p value
Age (years) 80.0 ± 4.1 62.6 ± 9.5  < 0.001 80.2 ± 4.0 63.8 ± 9.0  < 0.001
Sex    0.206    0.473
 Male 127 (68.3) 323 (73.4)   123 (69.1) 127 (72.6)  
 Female 59 (31.7) 117 (26.6)   55 (30.9) 48 (27.4)  
CCI     < 0.001    0.002
 Low 65 (34.9) 243 (55.2)   64 (36.0) 91 (52.0)  
 Moderate/severe 121 (65.1) 197 (44.8)   114 (64.0) 84 (48.0)  
 mFI 0.074 ± 0.068 0.046 ± 0.061  < 0.001 0.073 ± 0.067 0.050 ± 0.064  < 0.001
Number of analyzed lymph nodes    0.577    
  < 16 8 (4.3) 21 (4.7)   0 0  
 ≥16 178 (95.7) 419 (95.3)   178 175  
 Number of positive lymph nodes 1.75 ± 5.34 1.62 ± 5.90 0.546 1.70 ± 4.80 2.13 ± 8.04 0.738
 Tumor size (mm) 40.4 ± 25.9 38.9 ± 25.6 0.470 40.5 ± 25.5 41.3 ± 26.3  
Depth of tumor invasion    0.479    0.956
 T1 115 (61.8) 288 (65.5)   107 (60.1) 108 (61.7)  
 T2 26 (14.0) 49 (11.1)   26 (14.6) 22 (12.6)  
 T3 33 (17.7) 84 (19.1)   33 (18.5) 34 (19.4)  
 T4 12 (6.5) 19 (4.3)   12 (6.8) 11 (6.3)  
Lymph node metastasis    0.765    0.700
 Positive 51 (27.4) 112 (25.5)   49 (27.5) 46 (26.3)  
 Negative 135 (72.6) 328 (74.5)   129 (72.5) 129 (73.7)  
Histologic type    0.005    0.511
 Differentiated 116 (62.4) 220 (50.0)   111 (62.4) 115 (65.7)  
 Undifferenciated 70 (37.6) 220 (50.0)   67 (37.6) 60 (34.3)  
Lymphatic invasion    0.136    0.845
 Positive 110 (59.1) 231 (52.5)   106 (59.6) 106 (60.6)  
 Negative 76 (40.9) 209 (47.5)   72 (40.4) 69 (39.4)  
Venous invasion    0.004    0.973
 Positive 102 (54.8) 184 (41.8)   100 (56.2) 98 (56.0)  
 Negative 84 (45.2) 256 (58.2)   78 (43.8) 77 (44.0)  
Stage of disease    0.550    0.578
 I 124 (66.7) 308 (70.0)   116 (65.2) 119 (68.0)  
 II 39 (21.0) 76 (17.2)   39 (21.9) 31 (17.7)  
 III 23 (11.3) 56 (12.8)   23 (12.9) 25 (14.3)  
Type of gastrectomy    0.508    0.951
 Distal 131 (70.4) 325 (73.9)   125 (70.2) 125 (71.4)  
 Total 34 (18.3) 64 (14.5)   34 (19.1) 33 (18.9)  
 Proximal 21 (11.3) 51 (11.6)   19 10.7) 17 (9.7)  
Approach    0.476    0.101
 Open 71 (38.2) 183 (41.6)   67 (37.6) 82 (46.9)  
 Laparo 115 (61.8) 257 (58.4)   111 (62.4) 93 (53.1)  
Lymphadectomy    0.005    0.006
  < D2 136 (73.1) 293 (66.6)   130 (73.0) 103 (58.9)  
 D2 50 (26.9) 147 (33.4)   48 (27.0) 72 (41.1)  
Adjuvant chemotherapy     < 0.001     < 0.001
 Present 12 (6.5) 84 (19.1)   11 (6.2) 37 (21.1)  
 Absent 174 (93.5) 356 (80.9)   167 (93.8) 138 (78.9)  
Death from another disease     < 0.001    0.022
 Present 33 (17.7) 37 (8.4)   31 (17.4) 16 (9.1)  
 Absent 153 (82.3) 403 (91.6)   147 (82.6) 159 (90.9)  
Death from primary disease    0.189    0.342
 Present 23 (12.4) 39 (8.9)   23 (12.9) 17 (9.7)  
 Absent 163 (87.6) 401 (91.1)   155 (87.1) 158 (90.3)  
CAR 0.127 ± 0.342 0.066 ± 0.176  < 0.001 0.121 ± 0.340 0.066 ± 0.164 0.005
NLR 2.797 ± 1.677 2.464 ± 1.597 0.002 2.778 ± 1.647 2.366 ± 1.159 0.013
PLR 167.1 ± 87.7 160.3 ± 85.3 0.327 168.2 ± 87.9 152.4 ± 66.5 0.114
PNI 46.4 ± 5.8 50.4 ± 5.6  < 0.001 46.5 ± 5.8 50.1 ± 5.1  < 0.001
  1. Data are presented as the mean ± standard deviation or number (percentage) of patients
  2. CAR C-reactive protein-to-albumin ratio, CCI Charlson comorbidity index, EP elderly patient, mFI modified frailty index, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, PNI prognostic nutritional index, NEP non-elderly patient