Table 4 Univariate and multivariate analysis of prognostic indicators to predict disease-free survival and overall survival for rectal cancer patients

Gender (female vs. male)

0.536–1.358

0.504

0.332–1.567

0.409

0.546–1.496

0.694

0.294–1.632

0.401

Age (≦65 y/o vs. > 65 y/o)

0.532–1.313

0.436

0.681–3.732

0.283

0.450–1.194

0.212

0.296–1.729

0.457

Surgical method

0.001*

0.037*

0.024*

0.127

 RS vs. LS

1.176–4.016

0.013*

1.163–6.024

0.020*

0.846–2.967

0.015*

1.033–6.132

0.042*

 RS vs. Open surgery

1.071–3.261

0.028*

0.457–3.268

0.690

0.279–1.015

0.055

0.492–6.384

0.382

Tumor size (≦5 vs. > 5 cm)

1.111–3.303

0.018*

0.614–12.201

0.187

0.380–1.174

0.161

0.090–2.001

0.279

CRM involvement (no vs. yes)

2.505–7.788

< 0.001*

1.053–23.806

0.043*

1.236–4.427

0.009*

0.563–48.181

0.146

Tumor grade (WD/MD vs. PD)

1.345–6.403

0.007*

1.717–27.106

0.006*

1.143–6.217

0.023*

1.554–28.879

0.011*

LVI (no vs. yes)

1.357–3.318

0.001*

0.015–11.118

0.596

1.441–3.834

0.001*

0.012–1.890

0.144

PNI (no vs. yes)

1.699–4.288

< 0.001*

0.998–6.835

0.051

1.734–4.740

< 0.001*

0.625–5.266

0.273

pT stage (T1–2 vs. T3)

1.5744.502

< 0.001*

0.269–1.665

0.388

1.505–4.259

< 0.001*

0.290–2.202

0.665

Pathologic stage (stage 0-II vs. III)

1.429–3.496

< 0.001*

0.230–155.766

0.282

1.480–3.919

< 0.001*

1.497–178.914

0.022*

TRS (0–1 vs. 2–3)

1.331–4.864

0.005*

0.626–2.831

0.457

1.014–4.199

0.046*

0.400–2.157

0.864

pCR (yes vs. no)

1.563–12.478

0.005*

0.117–1.304

0.127

0.101–0.828

0.021*

0.135–1.585

0.220