Table 3 Factors affecting overall survival after resection on Cox univariate analysis
Number | Hazard ratio | P | |
|---|---|---|---|
Sex (male vs. female) | 143/90 | 0.812 (0.568, 1.159) | 0.251 |
Age (> 60 vs. ≤60) | 80/153 | 0.872 (0.597, 1.272) | 0.476 |
Primary tumour location (rectum vs. colon) | 86/147 | 0.886 (0.615, 1.276) | 0.516 |
Primary tumour T stage (T4 vs. T1–3) | 63/170 | 1.210 (1.072, 1.366) | 0.002 |
Primary tumour node status (N+ vs. N0) | 162/71 | 1.596 (1.064, 2.395) | 0.024 |
Number of liver metastases (> 4 vs. ≤4) | 70/163 | 1.290 (0.888, 1.876) | 0.181 |
Extent of liver metastases (bilobar vs. unilobar) | 127/106 | 1.338 (0.936, 1.912) | 0.110 |
Size of liver metastases (> 30 vs. ≤30 mm) | 85/148 | 1.700 (1.196, 2.415) | 0.003 |
Extent of hepatectomy (major vs. minor) | 81/152 | 1.114 (0.775, 1.602) | 0.559 |
Combined with RFA (yes vs. no) | 23/210 | 0.588 (0.274, 1.261) | 0.172 |
Margin status (R1 vs. R0) | 39/194 | 1.321 (0.838, 2.082) | 0.231 |
Initial chemotherapy (yes vs. no) | 133/100 | 0.940 (0.661, 1.337) | 0.731 |
Biologic agents used in initial chemotherapy (yes vs. no) | 57/176 | 0.931 (0.752, 1.153) | 0.511 |
Surgical strategy | |||
Sequential resection | 49 | 1 | |
Delayed resection | 98 | 0.612 (0.388, 0.967) | 0.035 |
Simultaneous resection | 86 | 0.735 (0.463, 1.168) | 0.193 |
Adjuvant chemotherapy (yes vs. no) | 171/62 | 0.683 (0.464, 1.005) | 0.053 |