Table 2 Treatment details and postoperative outcomes in the three groups

Initial chemotherapy

Yes/no

41/8

26/72

66/20

<0.001

0.340

<0.001

Biologic agents

(Yes/no)

17/32

10/88

30/56

<0.001

0.982

<0.001

Adjuvant chemotherapy

Yes/no

39/10

68/30

64/22

0.190

0.497

0.450

Hepatectomy

Major/minor

21/28

31/67

29/57

0.180

0.290

0.763

Combined with RFA

Yes/no

7/42

11/87

5/81

0.594

0.177

0.194

Hilar vascular clamp

Yes/no

46/3

82/16

66/20

0.082

0.011

0.237

Blood loss, ml (range)

200 (80-1400)

200 (70-1000)

200 (100-3200)

0.709

0.132

0.024

Differentiation of metastases

0.762

0.594

0.127

 Well/Moderate/Poor

3/39/7

7/81/10

6/62/18

Margin status

R0/R1

39/10

81/17

74/12

0.651

0.329

0.528

Any morbidity

0.514

0.382

0.016

 Grade 0

29

67

44

 Grade 1-2

12

20

19

 Grade 3-4

8

11

23

Overall morbidity, n (%)

20 (40.8)

31 (31.6)

42 (48.8)

0.270

0.369

0.017

Cumulative major complications, n (%)

8 (16.3)

11 (11.2)

23 (26.7)

0.385

0.166

0.007