Table 4 Univariate and multivariate analysis of overall survival (validation cohort, n = 247)
From: AGLR is a novel index for the prognosis of hepatocellular carcinoma patients: a retrospective study
| Clinical character | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| AGLR level (> 90 vs ≤ 90) | 2.47 (1.59–3.64) | < 0.001 | 1.82 (1.35–2.57) | < 0.001 |
| Age, years (> 60 vs ≤ 60) | 1.16 (0.77–1.76) | 0.460 | ||
| Gender (male vs female) | 1.49 (1.11–2.30) | 0.096 | ||
| Drinking (yes vs no) | 1.23 (0.88–1.71) | 0.207 | ||
| HBsAg (positive vs negative) | 1.10 (0.72–1.67) | 0.639 | ||
| AFP, ng/ml (> 20 vs ≤ 20) | 1.65 (1.13–2.65) | 0.011 | 1.07 (0.81–1.44) | 0.366 |
| Liver cirrhosis (yes vs no) | 1.03 (0.59–1.79) | 0.801 | ||
| Tumor size, cm (> 5 vs ≤ 5) | 2.11 (1.49–2.91) | < 0.001 | 1.69 (1.15–2.480) | 0.008 |
| Tumor number (multiple vs single) | 1.63 (1.22–2.54) | 0.013 | 1.20 (0.81–1.79) | 0.307 |
| TNM stage (III–IV vs I–II) | 2.33 (1.83–3.50) | < 0.001 | 1.39 (1.07–2.10) | 0.016 |
| MVI (yes vs no) | 2.81 (1.99–3.73) | < 0.001 | 2.30 (1.57–2.93) | < 0.001 |
| Recurrence (yes vs no) | 2.51 (1.64–3.51) | < 0.001 | 2.05 (1.46–2.79) | < 0.001 |