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Table 2 Correlation between clinical pathologic characteristics and AGLR level in HCC patients

From: AGLR is a novel index for the prognosis of hepatocellular carcinoma patients: a retrospective study

Variables AGLR level
Training cohort (n = 248) Validation cohort (n = 247)
 ≤ 90 n (%)  > 90 n (%) p value  ≤ 90 n (%)  > 90 n (%) p value
Age (years)
 ≤ 60 92 (46.2) 107 (53.8) 0.347 81 (41.3) 115 (58.7) 0.815
 > 60 19 (38.8) 30 (61.2)   22 (43.1) 29 (56.9)  
Gender       
 Female 18 (60.0) 12 (40.0) 0.073 18 (52.9) 16 (47.1) 0.152
 Male 93 (42.7) 125 (57.3)   85 (39.9) 128 (60.1)  
Drinking       
 No 62 (44.6) 77 (55.4) 0.958 58 (43.3) 76 (56.7) 0.583
 Yes 49 (45.0) 60 (55.0)   45 (39.8) 68 (60.2)  
HBsAg       
 Negative 14 (38.9) 22 (61.1) 0.444 17 (43.6) 22 (56.4) 0.794
 Positive 97 (45.8) 115 (54.2)   86 (41.3) 122 (58.7)  
AFP (ng/mL)       
 ≤ 20 54 (62.8) 32 (37.2)  < 0.001 43 (58.6) 30 (41.4)  < 0.001
 > 20 57 (35.2) 105 (64.8)   60 (34.5) 114 (65.5)  
Liver cirrhosis       
 No 8 (57.1) 6 (42.9) 0.337 10 (43.5) 13 (56.5) 0.856
 Yes 103 (44.0) 131 (56.0)   93 (41.5) 131 (58.5)  
Tumor size (cm)       
 ≤ 5 66 (65.3) 35 (34.7)  < 0.001 61 (56.5) 47 (43.5)  < 0.001
 > 5 45 (30.6) 102 (69.4)   42 (30.2) 97 (69.8)  
Tumor number       
 Single 90 (48.6) 95 (51.4) 0.035 84 (43.5) 109 (56.5) 0.272
 Multiple 21 (33.3) 42 (66.7)   19 (35.2) 35 (64.8)  
TNM stage       
 I-II 82 (68.9) 37 (31.1)  < 0.001 81 (57.4) 60 (42.6)  < 0.001
 III- IV 29 (22.5) 100 (77.5)   22 (20.8) 84 (79.2)  
Microvascular invasion       
 No 95 (52.2) 87 (47.8)  < 0.001 96 (46.2) 112 (53.8) 0.001
 Yes 16 (24.2) 50 (75.8)   7 (17.9) 32 (82.1)  
Recurrence       
 No 70 (47.0) 79 (53.0) 0.388 71 (45.2) 86 (54.8) 0.138
 Yes 41 (41.4) 58 (58.6)   32 (35.6) 58 (64.4)  
  1. AGLR, alkaline phosphatase plus gamma-glutamyl transpeptidase to lymphocyte ratio; HBsAg, hepatitis B surface antigen; AFP, alpha-fetoprotein; TNM, tumor-node-metastasis