Authors and publication year | Location | Patients age and gender | Tumor size (cm) | Case description | Patients outcomes |
---|---|---|---|---|---|
Dorobisz et al. [11] | Larynx | 75 years male | 1.4 cm | Moderately differentiated squamous cell carcinoma was involving the subglottic area, the submucosal layer of the glottis on the right side, and the tracheal mucosa. Leiomyosarcoma was found in the subglottic area | To date, the patient has no recurrent lesions |
Pongsuvareeyakul et al. [12] | Ovary | 65 years female | 17 | Two distinct components of sarcomatous and invasive epithelial elements found in a mature cystic teratoma of the ovary | Dead due to unrelated cause after 1 month |
Jang et al.[6] | Esophagus | 72 years male | 30 cm | The tumor consisted of pleomorphic spindle cells with mitosis and cell necrosis compatible with leiomyosarcoma Squamous severe dysplasia and focal stratified squamous epithelial invasion into the lamina propria were also noted compatible with squamous cell carcinoma | Two months' follow up showed no recurrence or distant metastasis |
Kara et al. (two cases) [13] | Larynx | 50 and 55 years males | Not mentioned | Case one: revealed spindle cell proliferation with mitotic figures. The squamous component of the tumor was well differentiated Case two: revealed leiomyosarcoma and squamous cell carcinoma on both vocal folds. Histological analysis showed spindle cell proliferation with mitotic figures, and a squamous component of the tumor was well differentiated | Case one: no recurrent lesion at 3 years follow up Case two: no recurrent lesion at 15-month follow up |
Tomidokoro et al. [14] | Larynx | 74 years male | left vocal fold was 1.2 × 0.9 × 0.8 cm right vocal fold was 1.2 × 0.8 × 0.7 cm | The left vocal fold tumor was moderate to poorly differentiated SCC The polypoid tumor of the right vocal fold was diagnosed as LMS | No recurrences at 9-month follow-up |
Dios et al. [9] | Oral Cavity | 67 years male | 1.5 cm on the soft palate and cobblestone area on lateral tongue | Soft palate lesion was diagnosed as LMS, and tongue lesion was diagnosed as SCC | LMS has no recurrence, but tongue SCC recurred at two and 19 months after the first surgery |
Eroğlu et al. [15] | Esophagus | 46 years male | 3 cm | The tumor was composed of spindle cells with eosinophilic cytoplasm and fusiform nuclei organized into bundles. Pleomorphic and giant cells and mitoses were present. Squamous cell carcinoma and leiomyosarcoma combination was reported | No recurrence at 16 months follow up |
Gaede et al. [16] | Esophagus | 56 years male | 8.5 × 6 × 3 cm, second tumor adjacent but distinctly separate was 2 cm mass with similar configuration | The lesion was diagnosed as LMS The second lesion showed marked atypia of the epithelium's entire thickness, indicating squamous cell carcinoma in situ, with foci of micro invasion | Unknown |