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Fig. 2 | BMC Surgery

Fig. 2

From: Reconstruction using a frozen autograft for a skull and humeral lesion of synchronous multicentric osteosarcoma after undergoing successful neoadjuvant chemotherapy: a case report and review of the literature

Fig. 2

Radiological and pathological findings of a bone lesion at the left distal femur. a, b Preoperative roentgenogram on the anteroposterior view (a), and the lateral view (b). c Intraosseous lesion combined with extraosseous lesion on MRI was observed, which was hypointense signal on T1 weighted images, and hyperintense signal on T2 weighted images. d Enhanced MRI revealed unevenly contrasted lesion on axial images. e Proliferation of pleomorphic spindle cells with nuclear atypia and brisk mitosis, producing a large amount of lace-like osteoid, were observed. White scale bar shows 100 µm

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