Skip to main content

Table 4 Diagnostic accuracy of absolute alteration of WBCC and CRP for anastomotic leakage after transthoracic esophageal resection

From: Prognostic value of inflammatory markers for detecting anastomotic leakage after esophageal resection

WBCC

ΔPOD

AUC

Cut-off [/nl]

Sensitivity

Specificity

NPV

PPV

Accuracy

p value

 

0 to 2

0.6

3

78%

36%

85%

26%

0.48

0.052

 

2 to 3

0.67

n/a

n/a

n/a

n/a

n/a

n/a

0.17

 

3 to 4

0.62

n/a

n/a

n/a

n/a

n/a

n/a

0.285

 

4 to 5

0.5

n/a

n/a

n/a

n/a

n/a

n/a

0.121

 

5 to 6

0.44

n/a

n/a

n/a

n/a

n/a

n/a

0.379

CRP

ΔPOD

AUC

Cut-off [mg/l]

Sensitivity (%)

Specificity (%)

NPV (%)

PPV (%)

Accuracy

p value

 

1 to 3

0.57

90

48

63

80.5

27.9

0.64

0.011*

 

2 to 3

0.59

0

54

61

81.7

29

0.64

0.024*

 

2 to 4

0.62

− 20

5

63

83.5

31.6

0.66

0.0003*

 

3 to 4

0.63

− 20

60

61

83.7

31

0.65

0.0001*

 

2 to 5

0.59

− 50

68

51

84.3

29

0.59

0.00001*

 

3 to 5

0.59

− 10

44

75

81.9

34.1

0.72

0.00008*

  1. WBCC: white blood cell count; CRP: C-reactive protein; NUn: Noble and Underwood; ΔPOD: change of value (WBCC or CRP) between postoperative days; AUC: Area under the curve; NPV: negative predictive value; PPV: positive predictive value; n/a: not available
  2. * p ≤ 0.05
Back to article page

BMC Surgery

ISSN: 1471-2482

Contact us