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Table 1 Clinicopathological variables associated with SRCs in LRC patients

From: Enhanced recovery after surgery nursing program, a protective factor for stoma-related complications in patients with low rectal cancer

Variables SRCs P-value
Yes No
Number, n (%) 77 (26.7) 211 (73.3)
Age (year), n (%) 0.048*
 ≥ 65 47 (61.0) 101 (47.9)
 < 65 30 (39.0) 110 (52.1)
Gender, n (%) 0.114
 Male 48 (62.3) 152 (72.0)
 Female 29 (37.7) 59 (28.0)
BMI (kg/m2), n (%) 0.031*
 ≥ 24.5 31 (40.3) 57 (27.0)
 < 24.5 46 (59.7) 154 (73.0)
ASA grade, n (%) 0.668
 I/II 49 (63.6) 140 (66.4)
 III/IV 28 (36.4) 71 (33.6)
Charlson Comorbidity Index 3.2 ± 0.8 2.5 ± 0.6  < 0.001
NRS 2002 score, n (%) 0.015*
 ≥ 3 17 (22.1) 23 (10.9)  
 < 3 60 (77.9) 188 (89.1)  
Active smoker, n (%) 1 0(13.0) 26 (12.3) 0.880
Heavy drinker, n (%) 8 (10.4) 22 (10.4) 0.993
Serum CEA (ng/mL), n (%) 0.686
 ≥ 5 36 (46.8) 93 (44.1)
 < 5 41 (53.2) 118 (55.9)
T stage, n (%) 0.409
 T1/2 23 (29.9) 74 (35.1)
 T3/4 54 (70.1) 13 7(64.9)
N stage, n (%) 0.163
 Negative 45 (58.4) 142 (67.3)
 Positive 32 (41.6) 69 (32.7)
TNM stage, n (%) 0.663
 I/II 46 (59.7) 120 (56.9)
 III 31 (40.3) 91 (43.1)
Pathologic differentiation, n (%) 0.936
 Well/moderate 62 (80.5) 169 (80.1)
 Poor/mucinous 15 (19.5) 42 (19.9)
Surgical approach, n (%) 0.371
 Laparoscopic 54 (70.1) 159 (75.4)
 Laparotomy 23 (29.9) 52 (24.6)
ERAS nursing program, n (%) 0.010*
 Yes 41 (53.2) 147 (69.7)
 No 36 (46.8) 64 (30.3)
Preoperative stoma localization, n (%) 10 (13.0) 51 (24.2) 0.040*
Operation time (min) 167.3 ± 37.4 155.9 ± 39.3 0.028*
Estimated blood loss (ml) 138.1 ± 50.5 146.5 ± 55.7 0.247
Height of stoma (mm) 10.7 ± 1.3 11.0 ± 1.2 0.067
Base area of stoma (cm2) 9.0 ± 1.1 8.7 ± 0.9 0.019*
  1. ERAS enhanced recovery after surgery, LRC low rectal cancer, SRCs stoma-related complications, BMI body mass index, ASA American Society of Anesthesiologists, NRS nutritional risk score, CEA carcinoembryonic antigen
  2. *P value < 0.05