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Table 2 Multivariate analyses of clinicopathological factors of patients with pancreatic cancer

From: Decreased mean platelet volume predicts poor prognosis in patients with pancreatic cancer

  

Overall survival

Disease specific survival

  

HR

95%CI

P value

HR

95%CI

P value

Age

 ≥ 75 vs. < 75 Years

1.518

0.665–3.466

0.32

1.607

0.646–3.996

0.31

Sex

Male vs. female

0.653

0.301–1.413

0.28

0.682

0.294–1.583

0.37

Histology

Well vs. others

0.890

0.500–1.584

0.69

0.876

0.465–1.649

0.68

Tumor location

Head vs. others

1.089

0.096–12.423

0.95

1.784

0.145–21.936

0.65

Operative procedure

PD vs. DP/TP

1.419

0.136–14.841

0.77

1.263

0.112–14.267

0.85

Tumor size

 ≥ 3 cm vs. < 3 cm

1.741

0.885–3.426

0.11

1.947

0.928–4.084

0.078

T category

T3 vs. T1/2

1.385

0.406–4.170

0.56

0.902

0.288–2.824

0.86

Lymph node metastasis

Present vs. absent

3.261

1.492–7.127

0.003

2.721

1.173–6.308

0.020

Lymphatic invasion

ly2/3 vs. ly0/1

1.975

1.009–3.868

0.047

1.749

0.837–3.651

0.14

Vascular invasion

v2/3 vs. v0/1

1.913

0.930–3.934

0.078

2.796

1.253–6.308

0.012

Intrapancreatic nerve invasion

ne2/3 vs. ne0/1

1.506

0.700–3.237

0.30

1.592

0.694–3.650

0.27

Residual tumor

R1 vs. R0

5.165

1.722–15.493

0.003

8.496

2.620–27.549

 < 0.001

Neoadjuvant chemotherapy

Present vs. absent

0.559

0.230–1.358

0.20

0.500

0.188–1.331

0.165

Adjuvant chemotherapy

Present vs. absent

0.346

0.153–0.783

0.011

0.318

0.129–0.783

0.013

CA19-9

 ≥ 66.3 vs. < 66.3 U/ml

2.452

1.159–5.187

0.019

1.928

1.061–4.319

0.044

MPV

 < 8.65 vs. ≥ 8.65 fL

2.247

1.007–5.012

0.048

3.578

1.411–9.074

0.007

  1. See Table 1 for the details of histology, surgical procedure, T category, lymphatic invasion, vascular invasion, intrapancreatic nerve invasion, and residual tumor
  2. CI confidence interval, HR hazard ratio, CA19-9 carbohydrate antigen 19-9, MPV mean platelet volume