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Table 2 Treatment options for AS by stage of disease [1, 34, 37, 38]

From: Bleeding “sarcomatosis” as a rare presentation of vascular graft-related angiosarcoma: case report and review of the literature

Stage Treatment
Localized disease Surgical resection with adequate margin (R0) and adjuvant radiotherapy with large doses (> 50 Gy)
Metastatic disease Chemotherapy with anthracyclines or taxanes as single cytotoxic drugs
Biological therapies with tyrosine kinase inhibitors showed benefits (under investigation)
Cytoreductive surgery and HIPEC for peritoneal metastases in the absence of systemic disease (under investigation)
  1. AS angiosarcoma, HIPEC hypertermic intraperitoneal chemotherapy