Stage | Treatment |
---|---|
Localized disease | Surgical resection with adequate margin (R0) and adjuvant radiotherapy with large doses (> 50 Gy) |
Metastatic disease | Chemotherapy with anthracyclines or taxanes as single cytotoxic drugs Biological therapies with tyrosine kinase inhibitors showed benefits (under investigation) Cytoreductive surgery and HIPEC for peritoneal metastases in the absence of systemic disease (under investigation) |