Table 5 Univariate analysis of perioperative risk factors of postoperative ND in patients with type A aortic dissection
Variable | ND (n = 101) | Non-ND (n = 220) | p |
|---|---|---|---|
Preoperative variables | |||
Age (year, \(\overline{x}\) ± s) | 56.70 ± 9.91 | 53.83 ± 9.75 | 0.422 |
Male (n, %) | 73 (73.7%) | 155 (69.8%) | 0.475 |
Education level (year, \(\overline{x}\) ± s) | 10.61 ± 5.30 | 11.23 ± 4.85 | 0.651 |
Tobacco use (n, %) | 52 (52.5%) | 108 (48.6%) | 0.521 |
Alcohol use (n, %) | 20 (20.2%) | 37 (16.7%) | 0.444 |
Barrier of hearing or language (n, %) | 3 (3.0%) | 7 (3.2%) | 1.000 |
Hypertension (n, %) | 87 (87.9%) | 168 (75.7%) | 0.012 |
Diabetes mellitus (n, %) | 23 (23.2%) | 36 (16.2%) | 0.134 |
COPD (n, %) | 4 (4.0%) | 6 (2.7%) | 0.505 |
Cerebrovascular disease history (n, %) | 26 (26.3%) | 34 (15.3%) | 0.020 |
Peripheral arterial disease (n, %) | 7 (7.1%) | 11 (5.0%) | 0.447 |
Renal dysfunction (n, %) | 9 (9.1%) | 8 (3.6%) | 0.043 |
LVEF < 0.4 (n, %) | 5 (5.1%) | 9 (4.1%) | 0.684 |
Preoperative neurological dysfunction (n, %) | 10 (9.9%) | 6 (2.7%) | 0.005 |
Preoperative intubation (n, %) | 9 (8.9%) | 7 (3.2%) | 0.024 |
Preoperative cardiac arrhythmia (n, %) | 8 (7.9%) | 11 (5%) | 0.273 |
Intraoperative variables | |||
Concomitant procedures (n, %) | |||
Bentall | 29 (28.7%) | 43 (19.5%) | 0.358 |
CABG | 15 (14.9%) | 12 (5.5%) | |
Bentall + CABG | 10 (9.9%) | 10 (4.5%) | |
CPB duration (min, \(\overline{x}\) ± s) | 259.93 ± 69.94 | 234.48 ± 49.24 | 0.009 |
Aortic cross-clamping duration (min, \(\overline{x}\) ± s) | 157.96 ± 37.17 | 153.25 ± 33.11 | 0.418 |
Circulatory arrest time (min, \(\overline{x}\) ± s) | 27.06 ± 6.05 | 25.33 ± 6.59 | 0.112 |
Type of cerebral perfusion (u-ACP, %) | 50 (49.5%) | 74 (33.6%) | 0.007 |
Nasopharyngeal temperature (℃, \(\overline{x}\) ± s) | 26.11 ± 1.49 | 26.60 ± 1.38 | 0.039 |
Blood transfusion > 1 L (n, %) | 25 (24.8%) | 34 (15.5%) | 0.046 |
Postoperative variables | |||
Postoperative drainage volume within 24 h (> 1 L) (n, %) | 15 (14.9%) | 16 (7.3%) | 0.033 |
AKI (n, %) | 16 (15.8%) | 25 (11.4%) | 0.264 |
Hemoglobin (g/L, \(\overline{x}\) ± s) | 93.25 ± 10.39 | 100.50 ± 9.35 | 0.180 |
Cardiac arrhythmia (n, %) | 21 (50.0%) | 36 (19.7%) | 0.335 |