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Table 4 The independent prognostic predictors for ICC

From: Preoperative risk grade predicts the long-term prognosis of intrahepatic cholangiocarcinoma: a retrospective cohort analysis

Variables Univariate analysis Multivariate analysis
HR 95% CI p HR 95% CI p
ALT ( 40 v < 40 U) 1.366 1.053–1.772 0.019 1.221 0.932–1.600 0.148
CEA ( 5 v < 5 U) 1.857 1.372–2.513 < 0.001 1.449 1.049–2.000 0.024
CA19-9 ( 37 v < 37 U) 1.619 1.226–2.137 0.001 1.454 1.090–1.940 0.011
Tumor number (multiple v single) 1.969 1.457–2.660 < 0.001 2.529 1.849–3.460 < 0.001
VI (yes v no) 2.053 1.534–2.747 < 0.001 1.402 1.036–1.897 0.029
Lymph node metastasis (yes v no) 2.227 1.714–2.894 < 0.001 1.720 1.302–2.274 < 0.001
PRG
 0 Reference    Reference   
 1 3.969 2.316–6.799 < 0.001 3.800 2.203–6.555 < 0.001
 2 8.617 5.038–14.739 < 0.001 7.585 4.357–13.206 < 0.001
  1. ICC intrahepatic cholangiocarcinoma, ALT alanine aminotransferase, CEA carcinoembryonic antigen, CA19-9 carbohydrate antigen 19-9, VI vascular invasion, PRG preoperative risk grade