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Table 5 Multiple cox regression analysis of survival after surgery

From: Long-term outcomes and prognostic factor analysis of resected Siewert type II adenocarcinoma of esophagogastric junction in China: a seven-year study

Variables Multivariate analysis P-value
HR 95%CI
Gender (male vs. female) 1.25 0.981–1.593 0.071
Pathology (adeno vs. mix) 1.066 0.864–1.314 0.55
Blood transfusion (no vs. yes) 0.63 0.471–0.843 0.002
Surgical approaches (left thoracotomy vs. transhiatal) 1.365 0.935–1.995 0.107
Tumor size (≤ 4cm vs. > 4cm) 0.728 0.582–0.912 0.006
 Postoperative hospital stays (≤ 10d vs. > 10d) 0.833 0.694–0.999 0.048
  PNLNR (> 1) 1 1 < 0.001
  PNLNR (= 0) 0.561 0.268–1.175 0.126
  PNLNR (≤  1) 0.773 0.507–1.180 0.233
 Perineuronal invasion (no vs. yes) 0.727 0.574–0.922 0.008
Lymphovascular invasion (no vs. yes) 0.899 0.721–1.121 0.346
pTNM stage IV 1 1 0.171
 Stage III 1.166 0.541–2.512 0.694
 Stage II 0.868 0.442–1.707 0.682
 Stage I 0.764 0.426–1.369 0.366
Serum CA199 (U/ml) (<37 vs. ≥37) 0.986 0.784–1.239 0.902
Serum CEA (ng/ml) (<5 vs. ≥5) 0.768 0.623–0.947 0.014
Serum CA242 (U/ml) (<20 vs. ≥20) 0.934 0.707–1.233 0.629
Serum CA125 (U/ml) (<35 vs. ≥35) 0.739 0.490–1.114 0.148
Adjuvant chemotherapy (no vs. yes) 1.478 1.214–1.800 < 0.001