Table 6 Uni- and Multivariate analysis to identify preoperative prognostic factors associated with overall survival in the 153 patients with LHL15 ≥ 0.9
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | p value | |
Age | 1.018 (0.98–1.06) | 0.40 | ||
Female | 0.4 (0.05–0.93) | 0.04 | 0.15 (0.034–0.65) | 0.011 |
BMI | 1.0 (0.90–1.12) | 0.39 | ||
Lymphocyte count (/mm3) | 1.0 (1.00–1.00) | 0.26 | ||
Neutrophil count (/mm3) | 1.0 (1.00–1.00) | 0.37 | ||
Platelet count (103/µl) | 1.0 (0.99–1.03) | 0.63 | ||
Albumin (g/dl) | 0.42 (0.20–0.86) | 0.017 | ||
Total bilirubin (mg/dl) | 0.76 (0.33–1.79) | 0.054 | ||
PT-INR | 4.30 (0.35–53.19) | 0.26 | ||
Child–Pugh B | 1.87 (0.74–4.72) | 0.18 | ||
AFP (ng/ml) | 1.0 (1.00–1.00) | 0.80 | ||
DCP (mAU/ml) | 1.0 (1.00–1.00) | 0.28 | ||
ICG R15 (%) | 1.03 (1.01–1.05) | 0.008 | ||
LHL15 | 0.52 (0.00–6.69) | 0.23 | ||
Tumor size (cm) | 1.13 (1.07–1.18) | < 0.001 | 1.13 (1.06–1.21) | < 0.001 |
Multiple tumor | 1.30 (0.69–2.43) | 0.41 | ||
Milan criteria beyond | 2.25 (1.26–4.00) | 0.006 | ||
PNI | 0.94 (0.90–0.98) | 0.003 | 0.92 (0.87–0.97) | 0.005 |
NLR | 1.08 (0.98–1.20) | 0.12 | ||
PLR | 1.0 (1.00–1.00) | 0.58 | ||
ALBI score | 2.08 (1.19–3.63) | 0.01 | ||