Table 3 Uni- and multivariate analysis to identify preoperative prognostic factors associated with overall survival in the 189 patients with HCC
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | p value | |
Age | 1.014 (0.98–1.048) | 0.41 | ||
Female | 0.3 (0.109–0.847) | 0.023 | 0.22 (0.076–0.62) | 0.005 |
BMI | 0.97 (0.89–1.06) | 0.50 | ||
Lymphocyte count (/mm3) | 1.0 (1.00–1.00) | 0.26 | ||
Neutrophil count (/mm3) | 1.0 (1.00–1.00) | 0.61 | ||
Platelet count (103/µl) | 1.0 (0.98–1.02) | 0.97 | ||
Albumin (g/dl) | 0.44 (0.26–0.76) | 0.003 | ||
Total bilirubin (mg/dl) | 0.26 (0.06–1.02) | 0.054 | ||
PT-INR | 4.30 (0.05–61.06) | 0.78 | ||
Child–Pugh B | 1.89 (0.45–7.93) | 0.38 | ||
AFP (ng/ml) | 1.0 (1.00–1.00) | 0.72 | ||
DCP (mAU/ml) | 1.0 (1.00–1.00) | 0.89 | ||
ICG R15 (%) | 1.03 (1.00–1.059) | 0.058 | ||
LHL15 | 2.57 (0.00–32,477,422) | 0.91 | ||
Tumor size (cm) | 1.14 (1.08–1.21) | < 0.001 | 1.11 (1.05–1.18) | < 0.001 |
Multiple tumor | 1.03 (0.37–2.29) | 0.94 | ||
Milan criteria beyond | 3.25 (1.51–6.99) | 0.002 | ||
PNI | 0.93 (0.88–0.99) | 0.02 | 0.92 (0.88–0.97) | 0.001 |
NLR | 1.09 (0.96–1.25) | 0.19 | ||
PLR | 1.0 (1.00–1.00) | 0.55 | ||
ALBI score | 2.22 (0.99–5.08) | 0.06 | ||