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Table 2 Univariate and multivariate analyses of the predictive indicators of POPF in patients who underwent pancreaticoduodenectomy

From: Combined prognostic nutritional index ratio and serum amylase level during the early postoperative period predicts pancreatic fistula following pancreaticoduodenectomy

Variables

Univariate analysis

Multivariate analysis

Odds ratio

95% CI

P value

Odds ratio

95% CI

P value

Age (≥ 70 vs. <  70)

0.704

0.374–1.324

0.276

   

Sex (male vs. female)

2.614

1266–5.396

0.009

2.514

0.916–6.902

0.074

Body mass index (≥ 25 vs. <  25)

2.738

1.252–5.987

0.012

0.896

0.265–3.025

0.896

Preoperative biliary drainage (present vs. absent)

2.005

1.060–3.791

0.032

3.313

1.216–9.053

0.019

Pancreatic texture of remnant pancreas (soft vs. hard)

10.088

3.791–26.848

<  0.001

2.607

0.533–12.745

0.237

Diameter of main pancreatic duct (≥ 3 mm vs. <  3 mm)

4.070

2.094–7.911

<  0.001

1.396

0.535–3.643

0.495

Operative time (≥ 480 min vs. <  480 min)

1.476

0.719–3.031

0.289

   

Intraoperative blood loss (≥ 1000 ml vs. <  1000 ml)

1.663

0.784–3.523

0.185

   

Pancreatic stent (internal stent vs. external stent)

0.401

0.182–0.887

0.024

0.378

0.121–1.178

0.094

Drain amylase level on POD 1 (≥ 4000 IU/l vs. <  4000 IU/l)

7.727

3.745–15.941

<  0.001

2.565

0.632–10.417

0.188

Serum CRP level on POD 3 (≥ 17.7 mg/dl vs. <  17.7 mg/dl)

12.226

5.782–25.850

<  0.001

6.929

2.458–19.534

< 0.001

Combination of PNIP3-P1 ratio and serum amylase level on POD 1

  

<  0.001

  

0.038

 score 0 vs. score 2

44.571

5.732–346.559

<  0.001

17.661

1.751–178.140

0.015

 score 1 vs. score 2

17.778

2.299–137.497

0.006

9.411

0.961–92.211

0.054

  1. CI confidence interval, BA Blumgart anastomosis, POD postoperative day, PNI prognostic nutritional index