Table 1 Reported cases of laryngeal rhabdomyosarcoma in adults
From: Adult laryngeal Embryonal Rhabdomyosarcoma: a case report and literature review
Author/YR | Age/sex | Primary Location | Symptoms or signs | Histologic subtype | Treatment | Status by end of follow up |
|---|---|---|---|---|---|---|
Mungan S [1], 2016 | 64/M | Glottic | Hoarseness for 2 months | Pleomorphic | Total laryngectomy with left radical neck dissection and radiotherapy (6MV photons in an Elekta Synergy Platform linear accelerator) | Alive & disease-free, 24 months |
Chiramel GK [6], 2015 | 70/M | Supraglottic | Hoarseness for 2 years | Pleomorphic | Chemotherapy (protocol was not provided) | Loss to follow-up |
Li Y [7], 2015 | 22/F | Glottic | Hoarseness for 1 month | Embryonal | Right cordectomy and selective neck dissection | Alive & disease-free, 60 months |
Russell JO [8], 2015 | 45/M | Glottic | Hoarseness for 11 months | Embryonal | Chemoradiation (vincristine, actinomycin, and cyclophosphamide combined with radiation dose of 50.4 Gy) | Alive, 34 months |
Kukwa W [4], 2011 | 33/M | Supraglottic | Longstanding hoarseness | Embryonal | Hemilaryngectomy and chemotherapy | Alive & disease-free, 62 months |
Leventhal DD [9], 2010 | 54/F | Glottic | Hoarseness for 9 months | Alveolar | Microsurgery by CO2 laser | Alive & disease-free, 12 months |
Pittore B [3], 2010 | 75/M | Glottic | Dysphonia for 1 year | Pleomorphic | Partial left laryngectomy | Alive & disease-free, 9 months |
Papacharalampous GX [10], 2009 | 83/F | Subglottic | Progressive dyspnoea for 3 months | Pleomorphic | Emergency tracheostomy and endoscopic tumour excision | dead (disease-free), 16 months |
Schrock A [2], 2007 | 60/M | Glottic | Hoarseness for 1 months | Pleomorphic | Total laryngectomy with a bilateral selective neck dissection | Alive & disease-free, 20 months |
66/M | Glottic | Dyspnea for 6 weeks and hoarseness for 2 weeks | Pleomorphic | Microsurgery by CO2 laser | Alive & disease-free, 20 months | |
Dikbas O [11], 2005 | 28/M | Glottic | Hoarseness for 15 days | Embryonal | Tracheostomy with biopcy and chemoradiation (cisplatin, vincristine, doxorubicin, and Cyclophosphamide; protocol of radiotherapy was not provided) | Alive & disease-free, 22 months |
Libera DD [12], 1999 | 66/M | Supraglottic | Hoarseness and sense of throat fullness | Embryonal (botryoid) | Partial laryngectomy | Alive & disease-free, 10 years |
Ruske DR [13], 1998 | 66/F | Supraglottic | Hoarseness and dyspnoea for 2 months | Pleomorphic | Total laryngectomy and radiotherapy (7040 cGys) | Alive & disease-free, 30 months |
Akyol MU [14], 1998 | 63/M | Supraglottic | Hoarseness and increasing dyspnea for 3 months | Pleomorphic | Total laryngectomy with right modified radical neck dissection and radiotherapy (6000 cGy to the tumor bed and 5000 cGy to the neck was given with cobalt 60 at a dose of 200 cGy/day) | Died of extensive lung metastases, 8 months |
Da Mosto MC [15], 1996 | 69/M | Glottic | Progrossive dysphonia for 7 months | Pleomorphic | Total laryngectomy and radiotherapy (6000 cGy over 6 weeks in 30 fractions) | Alive & disease-free, 24 months |
Balázs M [16], 1989 | 40/M | Supraglottic | Hoarseness several years | Embryoid (Botryoid) | Microsurgery | Alive & disease-free, 36 months |
Haerr RW [17], 1987 | 62/M | Supraglottic | Dysphagia several days | Alveolar | Total laryngectomy with left radical neck dissection and radiotherapy ((4000 cGy in 22 fractions) | Died of extensive distant metastases, 5 months |
Srinivasan U [18], 1979 | 55/M | Supraglottic | Hoarseness, dysphagia and a burning sensation in the throat for two months | Pleomorphic | Laryngectomy planned | Died prior to surgery of acute laryngeal obstruction |
Winter LK [19], 1978 | 72/M | Glottic | Hoarseness 2 months | Pleomorphic | Radical removal | Alive & disease-free, 9 months |
Frugoni (Verona) [20] P, 1976 | 33/M | Supraglottic | Hoarseness 3 months | Pleomorphic | Partial laryngectomy and radiotherapy (protocol was not provided) | Alive & disease-free, 6 years |
Hall-Jones J [21], 1975 | 54/M | Supraglottic | dramatically with a large tumour mass obstructing his laryngeal inlet | Embryonal | Total laryngectomy | Alive & disease-free, 15 months |
Rodriguez LA [22], 1970 | 57/M | Glottic | Acute respiratory distress | Pleomorphic | Total laryngectomy | No follow-up reported |