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Table 1 Demographics and clinical profiles of cases of GCT of the thyroid reported to date

From: Recurrent granular cell tumor of the thyroid: a case report and literature review

Author Year Sex Age (year) Location Size (cm) Surgical Method Positive Expression Negative Expression Follow-up (month)
Mahoney et al. [7] 1995 F 12 R 1.5 Lobectomy S-100 Tg, Vimentin, Ctn, Chromogranin, Epithelial membrane antigen 12
Paproski et al. [8] 2001 F 23 I 1.5 Isthmusectomy S-100, Tg 4
Milias et al. [9] 2004 F 43 L 2.5 Total Thyroidectomy S-100, NSE, Vimentin, Laminin, CD68 Tg, Cytokeratins Cam5.2, AE1\ AE3, Carcinoembryonic antigen, SMA, Ctn 0
Baloch et al. [10] 2005 F 47 L 2.5 Total Thyroidectomy S-100 Tg, TTF-1, Ctn, Chromogranin 0
Chang et al. [11] 2009 F 12 I 1.55 Isthmusectomy S-100, Vimentin Tg, TTF-1, Chromogranin A, Synaptophysin, Ctn, Cytokeratin 15
Espinosa-de-Los-Monteros-Franco et al. [12] 2009 M 21 L 1.8 Total Thyroidectomy S-100, Calretinin, Protein gene product 9.5 Tg, AE1\ AE3, TTF-1 6
Bowry et al. [13] 2011 F 36 R 0.8 Lobectomy S-100, CD68, Calretinin, Inhibin A Tg, AE1\ AE3, Cytokeratin 7, TTF-1, Synaptophysin, Chromogranin A, Ctn 0
Singh et al. [14] 2013 F 11 R 4 Biopsy S-100   0
Harp et al. [15] 2013 F 27 R 4.23 Rejected surgery S-100, CD68 Synaptophysin, Chromogranin 0
Chen et al. [16] 2014 F 14 R 3.3 Lobectomy S-100, CD68, NSE Tg, TTF-1, Ctn 12
  1. F female, M male, R right, L left, I isthmus;