Table 1 Demographics and clinical profiles of cases of GCT of the thyroid reported to date
From: Recurrent granular cell tumor of the thyroid: a case report and literature review
Author | Year | Sex | Age (year) | Location | Size (cm) | Surgical Method | Positive Expression | Negative Expression | Follow-up (month) |
|---|---|---|---|---|---|---|---|---|---|
Mahoney et al. [7] | 1995 | F | 12 | R | 1.5 | Lobectomy | S-100 | Tg, Vimentin, Ctn, Chromogranin, Epithelial membrane antigen | 12 |
Paproski et al. [8] | 2001 | F | 23 | I | 1.5 | Isthmusectomy | S-100, | Tg | 4 |
Milias et al. [9] | 2004 | F | 43 | L | 2.5 | Total Thyroidectomy | S-100, NSE, Vimentin, Laminin, CD68 | Tg, Cytokeratins Cam5.2, AE1\ AE3, Carcinoembryonic antigen, SMA, Ctn | 0 |
Baloch et al. [10] | 2005 | F | 47 | L | 2.5 | Total Thyroidectomy | S-100 | Tg, TTF-1, Ctn, Chromogranin | 0 |
Chang et al. [11] | 2009 | F | 12 | I | 1.55 | Isthmusectomy | S-100, Vimentin | Tg, TTF-1, Chromogranin A, Synaptophysin, Ctn, Cytokeratin | 15 |
Espinosa-de-Los-Monteros-Franco et al. [12] | 2009 | M | 21 | L | 1.8 | Total Thyroidectomy | S-100, Calretinin, Protein gene product 9.5 | Tg, AE1\ AE3, TTF-1 | 6 |
Bowry et al. [13] | 2011 | F | 36 | R | 0.8 | Lobectomy | S-100, CD68, Calretinin, Inhibin A | Tg, AE1\ AE3, Cytokeratin 7, TTF-1, Synaptophysin, Chromogranin A, Ctn | 0 |
Singh et al. [14] | 2013 | F | 11 | R | 4 | Biopsy | S-100 | Â | 0 |
Harp et al. [15] | 2013 | F | 27 | R | 4.23 | Rejected surgery | S-100, CD68 | Synaptophysin, Chromogranin | 0 |
Chen et al. [16] | 2014 | F | 14 | R | 3.3 | Lobectomy | S-100, CD68, NSE | Tg, TTF-1, Ctn | 12 |