Table 2 EORTC QOL-HN 35 scores were evaluated preoperatively (t1 in case group and t1’ in control group) and post-operatively (1-year follow up, t2 in case group and t2’ in control group). Mean (standard deviation), Median (interquartile range) and p values (Mann-Whitney U test) of the change in EORTC QOL-HN 35 scores over time between t1 and t2, and between t1’ and t2’
Changes in EORTC QOL-HN 35 score | EORTC QOL-HN 35 scores | p-value | |||||||
|---|---|---|---|---|---|---|---|---|---|
Case, n = 8 | Control, n = 14 | ||||||||
t1 (Mean) | t2 (Mean) | t2 − t1 (Mean) | t2 − t1 (Median) | t1’ (Mean) | t2’ (Mean) | t2’ − t1’ (Mean) | t2’ − t1’ (Median) | ||
Pain | 31.250 | 34.375 | 3.125 ± 5.786 | 0 (0–6.250) | 33.750 | 32.857 | −0.893 ± 3.144a | 0 (−6.250–0) | 0.1251 |
Swallowing | 25.0 | 28.125 | 3.125 ± 3.341 | 3.125 (0–6.250) | 31.25 | 60.714 | 29.464 ± 14.998 | 25.0 (18.750–43.750) | 0.0001 |
Sense | 25.0 | 28.125 | 3.125 ± 5.786 | 0 (0–6.250) | 25.0 | 35.714 | 10.714 ± 22.391 | 0 (0–12.50) | 0.7409 |
Speech | 25.0 | 29.167 | 4.167 ± 4.454 | 4.167 (0–8.333) | 26.189 | 52.379 | 26.190 ± 24.646 | 25.0 (8.333–4.167) | 0.0119 |
Social eating | 28.125 | 43.750 | 15.625 ± 13.774 | 9.375 (6.25–25.0) | 30.357 | 60.714 | 30.357 ± 14.052 | 25.0 (18.750–50.0) | 0.0197 |
Social contact | 25.0 | 43.750 | 18.75 ± 4.432 | 17.50 (15.0–22.5) | 25.0 | 52.571 | 27.571 ± 9.982 | 25.0 (20.0–35.0) | 0.039 |
Sexuality | 25.0 | 31.250 | 6.250 ± 11.573 | 0 (0–12.5) | 25.0 | 35.714 | 10.714 ± 18.898 | 0 (0–25.0) | 0.7409 |
Teeth | 31.250 | 37.50 | 6.250 ± 11.573 | 0 (0–12.5) | 39.286 | 46.429 | 7.143 ± 11.720 | 0 (0–25.0) | 0.8678 |
Open mouth | 37.50 | 37.50 | 0 | 0 | 39.286 | 50.0 | 10.714 ± 18.898 | 0 (0–25.0) | 0.1370 |
Dry mouth | 31.250 | 43.750 | 12.50 ± 13.363 | 12.50 (0–25.0) | 28.571 | 57.142 | 28.571 ± 9.078 | 25.0 (25.0–25.0) | 0.0082 |
Sticky saliva | 25.0 | 25.750 | 0.750 ± 0.886 | 0.50 (0–1.50) | 25.0 | 39.286 | 14.286 ± 12.839 | 25.0 (0–25.0) | 0.1503 |
Cough | 25.0 | 25.0 | 0 | 0 | 25.0 | 28.571 | 3.571 ± 9.078 | 0 | 0.3603 |
Questionnaire 31–35 summed up | 50.0 | 52.5 | 2.50 ± 3.273 | 1.25 (0–5.0) | 51.429 | 51.429 | 0 | 0 | 0.1094 |