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Table 4 Logistic Regression Analysis of factors affecting POPF

From: The individualized selection of Pancreaticoenteric anastomosis in Pancreaticoduodenectomy

Parameter

Univariate Analysis

P

Multivariate Analysis

P

Odds Ratio

95% CI

Odds Ratio

95% CI

Gender

  

0.153

   

 Female

1

     

 Male

0.771

0.539–1.102

    

Gland texture

  

< 0.001

  

< 0.001

 Hard

1

  

1

  

 Soft

2.787

1.877–4.138

 

3.191

1.695–6.008

 

Pathology

  

< 0.001

  

0.15

 PDAC or CP

1

  

1

  

 Others

2.635

1.704–4.077

 

1.605

0.842–3.058

 

pancreatic duct diameter

 

< 0.001

  

< 0.001

  > 3 mm

1

  

1

  

  ≤ 3 mm

4.14

2.601–6.591

 

3.928

2.217–6.961

 

Intraoperative blood loss

 

0.814

   

  ≤ 400 ml

1

     

  > 400 ml

1.076

0.582–1.992

    

Age

  

0.725

   

  < 70

1

     

  ≥ 70

0.913

0.550–1.516

    

BMI

  

< 0.001

  

0.001

  < 25

1

  

1

  

  ≥ 25

2.068

1.421–3.008

 

1.976

1.326–2.945

 

ASA score

  

0.4

   

 1-2

1

     

 3-4

0.743

0.303–1.134

    

Preoperative jaundice

 

0.608

   

 No

1

     

 Yes

0.912

0.640–1.299

    

Alcohol abuse

  

0.482

   

 No

1

     

 Yes

1.17

0.755–1.813

    

Diabetes mellitus

 

0.462

   

 No

1

     

 Yes

1.19

0.748–1.894

    

Previous abdominal surgery history

0.913

   

 No

1

     

 Yes

0.976

0.626–1.521

    

Preoperative biliary decompression

0.176

   

 No

1

     

 Yes

1.302

0.888–1.910

    

Operation time

  

0.028

  

0.04

  ≤ 330 min

1

  

1

  

  > 330 ml

1.622

1.055–2.494

 

1.635

1.022–2.617

 

Intraoperative RBC transfusion

 

0.273

   

 No

1

     

 Yes

1.345

0.791–2.286

    

Pancraticoenteric anastomosis method

0.037

  

0.001

 Pancreticojejunostomy (PJ)

1

  

1

  

 Pancreticogastrostomy (PG)

1.529

1.025–2.279

 

0.323

0.163–0.639

 

Combined with vascular resection

 

0.232

   

 No

1

     

 Yes

0.531

0.188–1.498

    
  1. PDAC pancreatic ductal adenocarcinoma;CP: chronic pancreatitis, BMI body weight index, ASA American Society of Anaesthesiologists