Fig. 1

A 21-year-old woman, she has no symptom and was admitted to our hospital because of a mediastinal mass found on a fortuitous CT scan. Contrasted chest CT showed a well-defined and homogeneous enhanced mass in the anterior mediastinum (a-c). The mass was whole resected by Video-assisted thoracoscopic surgery and confirmed hyaline vascular type Castleman disease. Histopathologic sections showed that capillary proliferation with perivascular hyalinization in the follicular and interfollicular, with a mixed inflammatory infiltrate of numerous small lymphocytes and plasma cells. (d, Hematoxylin and eosin, × 100). Chemotherapy was not suggested. She had been alive without recurrence for 5 years