Skip to main content

Table 2 Univariate and multivariate analysis for evaluating preoperative risk factors associated with POPF

From: Pancreas-visceral fat CT value ratio and serrated pancreatic contour are strong predictors of postoperative pancreatic fistula after pancreaticojejunostomy

Variables

non-POPF, BL (n = 235)

POPF Grade BC (n = 27)

P-value (Univariate)

Odd’s ratio (95% CI)

P-value (Multivariate)

Age

67.0 (25–89)

67.0 (25–89)

0.094

  

Gender: M / F

137/98

21/6

0.050

–

–

Diagnosis: (PDAC/non-PDAC)

113/122

7/20

0.029

–

–

Preoperative diabetes mellitus (yes/no)

81/154

6/21

0.201

  

BMI (kg/m2)

21.1 (14.9–40.0)

23.7 (14.1–31.0)

0.002

–

–

Chemoradiotherapy (yes/no)

94/141

4/23

0.010

0.25 (0.08–0.80)

0.019

MPD diameter on CT (mm)

3.0 (1.0–13.6)

2.5 (1.0–6.0)

0.160

  

Pancreatic parenchymal thickness on CT *(mm)

13.5 (4.5–27.0)

14.0 (25.0–25.0)

0.348

  

Pancreatic parenchymal CT value (HU)

38.5 (10.2–56.5)

35.8 (9.7–54.8)

0.028

–

–

Visceral fat CT value (HU)

−97.5 (−123.1- − 100.8)

-100.8 (− 120.7 - -23.0)

0.025

–

–

pancreas-visceral fat CT value ratio

−0.40 (−1.21- -0.117)

−0.35 (−0.42–0.09)

0.00025

2891.5 (17.6–473,225.1)

0.002

Type of parenchymal contour (Serrated/smooth)

24/211

10/17

< 0.001

3.11 (1.20–8.06)

0.020

  1. Parenchymal thickness = the thickness of the pancreas (mm) - MPD diameter (mm), at the planned cut line
  2. CI confidence interval, PDAC pancreatic ductal adenocarcinoma, IPMN intraductal papillary mucinous neoplasm, BMI body mass index, MPD main pancreatic duct, PPPD pylorus-preserving pancreaticoduodenectomy, SSPPD subtotal stomach-preserving pancreaticoduodenectomy, POPF postoperative pancreatic fistula, BL biochemical leak, Statistical analysis: Mann- Whitney U test for contentious variables. χ2 analysis for discrete variables