Comparisons of perventricular device closure, conventional surgical repair, and transcatheter device closure in patients with perimembranous ventricular septal defects: a network meta-analysis

Table 2 Results of comparisons with tests of inconsistency

Title/Subtitle	PDC versus CSR			TDC versus CSR			TDC versus PDC			P for inconsistency
Title/Subtitle	RR	95% CI	P	RR	95% CI	P	RR	95% CI	P	P for inconsistency
Perioperative indexes
Procedural success rate	0.98	0.96–0.99	0.03	0.98	0.97–1.00	0.11	1.00	0.98–1.02	0.75	0.42
Residual shunt	0.61	0.40–0.93	0.02	0.79	0.51–1.22	0.29	1.29	0.73–2.29	0.38	0.19
II degree AVB	1.52	0.61–3.81	0.36	0.59	0.25–1.42	0.24	0.39	0.11–1.32	0.13	0.91
Complete AVB	0.90	0.43–1.88	0.78	0.98	0.46–2.10	0.96	1.08	0.42–2.82	0.86	0.40
RBBB	0.53	0.30–0.94	0.03	0.36	0.21–0.62	< 0.01	0.68	0.31–1.47	0.33	NA
Procedure–induced AR	0.53	0.28–1.01	0.05	1.30	0.63–2.69	0.47	2.45	1.33–4.49	< 0.01	0.32
Procedure–induced TR	0.55	0.33–0.92	0.02	0.56	0.19–1.66	0.29	1.04	0.34–3.19	0.95	NA
Incision complications	0.50	0.26–0.96	0.04	0.39	0.13–1.20	0.10	0.77	0.23–2.61	0.67	0.95
Pericardial effusion	0.47	0.29–0.76	< 0.01	NA	NA	NA	NA	NA	NA	NA
Follow–up data
Residual shunt	0.25	0.14–0.42	< 0.01	0.29	0.11–0.79	0.02	1.19	0.38–3.68	0.78	NA
RBBB	0.50	0.34–0.72	< 0.01	0.38	0.27–0.55	< 0.01	0.77	0.46–1.30	0.33	NA
Procedure–induced AR	0.72	0.19–2.72	0.62	1.52	0.27–8.51	0.64	2.12	0.36–12.42	0.40	0.49
Procedure–induced TR	0.31	0.19–0.48	< 0.01	0.48	0.09–2.50	0.39	1.58	0.29–8.69	0.60	NA

PDC perventricular device closure; CSR conventional surgical repair; TDC transcatheter device closure; RR relative risk; NA not available; AVB atrioventricular block; RBBB right bundle branch block; AR aortic regurgitation; TR tricuspid regurgitation

ISSN: 1471-2482