Table 1 Reported cases of rhabdomyosarcoma of the liver in adults
From: Pleomorphic rhabdomyosarcoma of the liver in an adult: a rare case report
Authors | Year | Age, years | Sex | Extent of liver involvement | Histology | Treatment | Outcome |
|---|---|---|---|---|---|---|---|
Miller and Pack [4] | 1956 | Total right hepatic lobectomy | |||||
Goldman and Freiedman [5] | 1969 | 65 | Male | Autopsy: right lobe contained an ovoid tumor measuring 35 × 15 × 10 cm | Embryonal/alveolar | Symptomatic treatment without any surgical procedure or chemotherapy | Died 3 months from initial symptoms |
Watanabe et al. [6] | 1983 | 70 | Male | Autopsy: yellowish-brown multinodular tumors up to 5 cm in diameter in right lobe | Pleomorphic | Symptomatic treatment without any surgical procedure or chemotherapy | Died 8 months from initial symptoms |
McArdle et al. [7] | 1989 | 53 | Male | Large mass occupied the entire right lobe | Embryonal | Surgical resection | Died 3 months from initial symptoms |
Akasofu et al. [8] | 1999 | 52 | Male | Autopsy: 19- × 12- × 11-cm tumor occupied almost the entire right lobe; it was not encapsulated and had invaded the right adrenal gland, diaphragm, bilateral hepatic ducts, and inferior vena cava | Symptomatic treatment without any surgical procedure or chemotherapy | Died 2.5 months from initial symptoms | |
Schoofs et al. [9] | 2011 | 59 | Female | Alveolar | Primary surgical resection + chemotherapy (doxorubicin/ifosfamide) | Initial good response to chemotherapy and stable disease at 12 months after diagnosis; died 31 months after the first symptoms | |
Aassab et al. [10] | 2012 | 25 | Male | Lesion in the right lobe of the liver measuring 136 mm | Embryonal | Biopsy followed by chemotherapy: doxorubicin, ifosfamide, and vincristine | Died after 3 months from initial symptoms |
Arora et al. [11] | 2016 | 67 | Male | 14.5- × 12.3- × 9.1-cm lesion involving left hepatic lobe. Large component of lesion was seen bulging into the left subhepatic space | Embryonal | Left hepatic lobectomy followed by adjuvant chemotherapy: doxorubicin, ifosfamide, and vincristine | At 24 months of follow-up, patients free from local recurrence and distant metastasis. |
Yin et al. [12] | 2018 | 66 | Female | Large mass measuring about 20 × 15 cm in the right lobe of the liver | Pleomorphic | Emergency laparotomy for hemostasis and right hepatic lobectomy without adjuvant chemotherapy | Died 3 months from surgery |
Present case | 2019 | 73 | Female | 12- × 10-cm lesion involving right hepatic lobe | Pleomorphic | Primary surgical resection + chemotherapy (trabectedin) | Died 6 months from surgery |