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Table 6 Multivariate analyses contributing to overall survival and tumor-free survival rate

From: Comparison of open liver resection and RFA for the treatment of solitary 3–5-cmhepatocellular carcinoma: a retrospective study

Variables

Hazard ratio

95% CI

P-value

Prognostic factors for overall survival

NLR ≥ 4

1.453

1.072–2.287

0.020

AFP ≥400 ng/ml

Intra-operative blood loss ≥ 400 ml

1.864

1.219

1.021–3.210

0.829–2.083

0.102

0.398

Histological grading

 Well

   

 Moderate

2.211

1.806–3.127

0.046

 Poor

2.680

1.346–4.632

<0.001

Tumor located central

1.458

1.091–1.762

0.469

Microvascular invasion

2.209

1.210–3.290

0.016

Treatment modality (Resection/RFA)

1.542

1.105–3.026

0.895

Prognostic factors for tumor-free survival

Platelet <100*10^9/L

1.782

1.142–2.891

0.142

NLR ≥ 4

1.374

1.201–2.347

<0.001

Microvascular invasion

1.618

1.082–2.289

0.015

Treatment modality (Resection/RFA)

1.762

1.052–2.217

0.651

  1. NLR Neutrophil-lymphocyte ratio, AFP Alpha-fetoproteinCox regression was used in multivariate analysis